Georg Nagel
Overview
Explore the profile of Georg Nagel including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
80
Citations
7223
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Duan X, Zhang C, Wu Y, Ju J, Xu Z, Li X, et al.
Nat Commun
. 2025 Jan;
16(1):559.
PMID: 39789018
Optogenetics is a valuable tool for studying the mechanisms of neurological diseases and is now being developed for therapeutic applications. In rodents and macaques, improved channelrhodopsins have been applied to...
2.
Ding M, Zhou Y, Becker D, Yang S, Krischke M, Scherzer S, et al.
Nature
. 2024 Aug;
633(8031):872-877.
PMID: 39198644
Early plant responses to different stress situations often encompass cytosolic Ca increases, plasma membrane depolarization and the generation of reactive oxygen species. However, the mechanisms by which these signalling elements...
3.
Schmidt A, Allmann S, Schwarzenbach C, Snyder P, Chen J, Nagel G, et al.
Nucleic Acids Res
. 2024 May;
52(12):6945-6963.
PMID: 38783095
Cellular senescence, a major driver of aging, can be stimulated by DNA damage, and is counteracted by the DNA repair machinery. Here we show that in p16INK4a-deficient cells, senescence induction...
4.
Strauss J, Deng L, Gao S, Toseland A, Bachy C, Zhang C, et al.
Nat Microbiol
. 2023 Oct;
8(11):2050-2066.
PMID: 37845316
Microbial rhodopsins are photoreceptor proteins that convert light into biological signals or energy. Proteins of the xanthorhodopsin family are common in eukaryotic photosynthetic plankton including diatoms. However, their biological role...
5.
Lin F, Tang R, Zhang C, Scholz N, Nagel G, Gao S
Pflugers Arch
. 2023 Sep;
475(12):1375-1385.
PMID: 37670155
Water transport through water channels, aquaporins (AQPs), is vital for many physiological processes including epithelial fluid secretion, cell migration and adipocyte metabolism. Water flux through AQPs is driven by the...
6.
Konrad K, Gao S, Zurbriggen M, Nagel G
Annu Rev Plant Biol
. 2023 May;
74:313-339.
PMID: 37216203
Optogenetics is a technique employing natural or genetically engineered photoreceptors in transgene organisms to manipulate biological activities with light. Light can be turned on or off, and adjusting its intensity...
7.
Holer S, Degreif D, Stix F, Yang S, Gao S, Nagel G, et al.
PLoS One
. 2023 Apr;
18(4):e0280711.
PMID: 37053213
Channelrhodopsin 2 (ChR2) and its variants are the most frequent tools for remote manipulation of electrical properties in cells via light. Ongoing attempts try to enlarge their functional spectrum with...
8.
Vom Dahl C, Muller C, Berisha X, Nagel G, Zimmer T
Membranes (Basel)
. 2022 Oct;
12(10).
PMID: 36295666
Voltage-gated sodium (Na) channels respond to short membrane depolarization with conformational changes leading to pore opening, Na influx, and action potential (AP) upstroke. In the present study, we coupled channelrhodopsin-2...
9.
Zhang Y, Benz P, Stehle D, Yang S, Kurz H, Feil S, et al.
Open Biol
. 2022 Aug;
12(8):220058.
PMID: 35975649
Cyclic guanosine monophosphate (cGMP) signalling plays a fundamental role in many cell types, including platelets. cGMP has been implicated in platelet formation, but mechanistic detail about its spatio-temporal regulation in...
10.
Tian Y, Gao S, Nagel G
Methods Mol Biol
. 2022 Jul;
2501:325-338.
PMID: 35857236
Rhodopsins with enzymatic activity were found in microbes, in 2004 hypothetically from sequence data and since 2014 by experimental proof. So far three different types are known: light-activated guanylyl cyclase...