Geoffrey Hutinet
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Explore the profile of Geoffrey Hutinet including associated specialties, affiliations and a list of published articles.
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22
Citations
350
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Recent Articles
11.
Hoetzinger M, Nilsson E, Arabi R, Osbeck C, Pontiller B, Hutinet G, et al.
Environ Microbiol
. 2021 Jun;
23(8):4576-4594.
PMID: 34190387
Phage predation constitutes a major mortality factor for bacteria in aquatic ecosystems, and thus, directly impacts nutrient cycling and microbial community dynamics. Yet, the population dynamics of specific phages across...
12.
Kot W, Olsen N, Nielsen T, Hutinet G, de Crecy-Lagard V, Cui L, et al.
Nucleic Acids Res
. 2020 Sep;
48(18):10383-10396.
PMID: 32941607
In the constant evolutionary battle against mobile genetic elements (MGEs), bacteria have developed several defense mechanisms, some of which target the incoming, foreign nucleic acids e.g. restriction-modification (R-M) or CRISPR-Cas...
13.
Hutinet G, Kot W, Cui L, Hillebrand R, Balamkundu S, Gnanakalai S, et al.
Nat Commun
. 2019 Dec;
10(1):5442.
PMID: 31784519
Genome modifications are central components of the continuous arms race between viruses and their hosts. The archaeosine base (G), which was thought to be found only in archaeal tRNAs, was...
14.
Crippen C, Lee Y, Hutinet G, Shajahan A, Sacher J, Azadi P, et al.
J Virol
. 2019 Sep;
93(23).
PMID: 31511377
Several reports have demonstrated that bacteriophage DNA is refractory to manipulation, suggesting that these phages encode modified DNA. The characterized phages fall into two phylogenetic groups within the : the...
15.
Ngazoa-Kakou S, Shao Y, Rousseau G, Addablah A, Tremblay D, Hutinet G, et al.
Microbiol Resour Announc
. 2019 Feb;
8(5).
PMID: 30714038
The lytic Escherichia coli siphophage BRET was isolated from a chicken obtained at a local market in Abidjan, Côte d'Ivoire. Its linear genome sequence consists of 59,550 bp (43.4% GC...
16.
Yuan Y, Hutinet G, Valera J, Hu J, Hillebrand R, Gustafson A, et al.
Mol Microbiol
. 2018 Aug;
110(3):469-483.
PMID: 30159947
The 7-deazapurine derivatives, 2'-deoxy-7-cyano-7-deazaguanosine (dPreQ ) and 2'-deoxy-7-amido-7-deazaguanosine (dADG) are recently discovered DNA modifications encoded by the dpd cluster found in a diverse set of bacteria. Here we identify the...
17.
Hutinet G, Besle A, Son O, McGovern S, Guerois R, Petit M, et al.
Front Microbiol
. 2018 May;
9:743.
PMID: 29740405
Bacteriophages are remarkable for the wide diversity of proteins they encode to perform DNA replication and homologous recombination. Looking back at these ancestral forms of life may help understanding how...
18.
Hutinet G, Swarjo M, de Crecy-Lagard V
RNA Biol
. 2016 Dec;
14(9):1175-1184.
PMID: 27937735
Seven-deazapurine modifications were thought to be highly specific of tRNAs, but have now been discovered in DNA of phages and of phylogenetically diverse bacteria, illustrating the plasticity of these modification...
19.
Thiaville J, Flood J, Yurgel S, Prunetti L, Elbadawi-Sidhu M, Hutinet G, et al.
ACS Chem Biol
. 2016 Jun;
11(8):2304-11.
PMID: 27294475
DUF1537 is a novel family of kinases identified by comparative genomic approaches. The family is widespread and found in all sequenced plant genomes and 16% of sequenced bacterial genomes. DUF1537...
20.
Thiaville J, Kellner S, Yuan Y, Hutinet G, Thiaville P, Jumpathong W, et al.
Proc Natl Acad Sci U S A
. 2016 Mar;
113(11):E1452-9.
PMID: 26929322
The discovery of ∼20-kb gene clusters containing a family of paralogs of tRNA guanosine transglycosylase genes, called tgtA5, alongside 7-cyano-7-deazaguanine (preQ0) synthesis and DNA metabolism genes, led to the hypothesis...