Geoffrey B McCowage
Overview
Explore the profile of Geoffrey B McCowage including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
250
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0
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Recent Articles
1.
Valvi S, Manoharan N, Mateos M, Hassall T, Ziegler D, McCowage G, et al.
Med J Aust
. 2024 May;
220(10):533-538.
PMID: 38699949
Introduction: The main mission of the Australian and New Zealand Children's Haematology and Oncology Group (ANZCHOG) is to develop and facilitate local access to the world's leading evidence-based clinical trials...
2.
Jackson E, Duchatel R, Staudt D, Persson M, Mannan A, Yadavilli S, et al.
Cancer Res
. 2023 May;
PMID: 37145169
Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are the most lethal of childhood cancers. Palliative radiotherapy is the only established treatment, with median patient survival of 9-11...
3.
In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer
Lau L, Mayoh C, Xie J, Barahona P, Mackenzie K, Wong M, et al.
EMBO Mol Med
. 2021 Dec;
14(4):e14608.
PMID: 34927798
Biomarkers which better match anticancer drugs with cancer driver genes hold the promise of improved clinical responses and cure rates. We developed a precision medicine platform of rapid high-throughput drug...
4.
Harrison D, Chi Y, Tian J, Hingorani P, Mascarenhas L, McCowage G, et al.
Cancer Med
. 2020 Dec;
10(3):857-866.
PMID: 33340280
Background: Strategies to optimize management in rhabdomyosarcoma (RMS) include risk stratification to assign therapy aiming to minimize treatment morbidity yet improve outcomes. This analysis evaluated the relationship between complete metabolic...
5.
Hsu K, Middlemiss S, Saletta F, Gottschalk S, McCowage G, Kramer B
Cancer Gene Ther
. 2020 Sep;
28(3-4):321-334.
PMID: 32873870
Chimeric Antigen Receptor (CAR) T-cell therapy, as an approved treatment option for patients with B cell malignancies, demonstrates that genetic modification of autologous immune cells is an effective anti-cancer regimen....
6.
Kamili A, Gifford A, Li N, Mayoh C, Chow S, Failes T, et al.
Br J Cancer
. 2020 Jan;
122(5):680-691.
PMID: 31919402
Background: Predictive preclinical models play an important role in the assessment of new treatment strategies and as avatar models for personalised medicine; however, reliable and timely model generation is challenging....
7.
Osorio D, Patel N, Ji L, Sposto R, Stanek J, Gardner S, et al.
J Neurooncol
. 2018 Nov;
140(3):717-725.
PMID: 30392092
Background: The dismal outcome in children with high-grade brainstem gliomas (BSG) accentuates the need for effective therapeutic strategies. We investigated the role of intensive, including marrow-ablative, chemotherapy regimens in the...
8.
Kamboj A, Hallwirth C, Alexander I, McCowage G, Kramer B
BMC Bioinformatics
. 2017 Jun;
18(1):305.
PMID: 28623888
Background: The analysis of viral vector genomic integration sites is an important component in assessing the safety and efficiency of patient treatment using gene therapy. Alongside this clinical application, integration...
9.
Green D, Merchant T, Billups C, Stokes D, Broniscer A, Bartels U, et al.
Int J Radiat Oncol Biol Phys
. 2015 Aug;
93(1):47-53.
PMID: 26279023
Purpose: The treatment of children with embryonal brain tumors (EBT) includes craniospinal irradiation (CSI). There are limited data regarding the effect of CSI on pulmonary function. Methods: Protocol SJMB03 enrolled...
10.
Kalra M, Heath J, Kellie S, Dalla Pozza L, Stevens M, Swamy S, et al.
J Pediatr Hematol Oncol
. 2015 Jun;
37(6):e341-6.
PMID: 26056795
Background: Management of low-grade gliomas (LGG) can be a challenge, particularly when not resectable and refractory or recurrent following standard treatments. We undertook a retrospective analysis of 2 institutions' experiences...