David S Ziegler
Overview
Explore the profile of David S Ziegler including associated specialties, affiliations and a list of published articles.
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Articles
147
Citations
3120
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Recent Articles
1.
Mateos M, Ajuyah P, Fuentes-Bolanos N, El-Kamand S, Barahona P, Altekoester A, et al.
Neuro Oncol
. 2025 Mar;
PMID: 40072012
Background: Factors that drive the development of diffuse midline gliomas (DMG) are unknown. Our study aimed to determine the prevalence of pathogenic/likely pathogenic (P/LP) germline variants in pediatric patients with...
2.
Pereira R, Mackay A, Grabovska Y, Bradley A, Bloom T, Nicoll J, et al.
Clin Cancer Res
. 2025 Mar;
PMID: 40063504
Background: High-grade gliomas (HGG) occur in any central nervous system (CNS) location and any age. HGGs in teenagers/young adults (TYA) are understudied. This project aimed to characterise these tumours to...
3.
Barlow-Stewart K, Courtney E, Cowley M, Ebzery C, Fuentes Bolanos N, Gifford A, et al.
NPJ Genom Med
. 2025 Feb;
10(1):12.
PMID: 39962063
In pediatric cancer precision medicine clinical trials settings, parents proactively seeking treatment and answers to causation may request return of their child's raw data and/or biospecimen. To satisfy such requests,...
4.
Upton D, Liu J, George S, Valvi S, Ung C, Rayner B, et al.
Neuro Oncol
. 2025 Feb;
PMID: 39935375
Background: Diffuse midline glioma, characterised by H3K27 alteration (DMG), is the predominant high-grade glioma in children. It commonly originates in the brainstem, yet effective treatments for these patients remain elusive....
5.
Nysom K, Kilburn L, Leary S, Landi D, de Vos-Kerkhof E, Perreault S, et al.
Neuro Oncol
. 2024 Dec;
PMID: 39700439
Background: Due to their anatomical locations, optic pathway gliomas (OPGs) can rarely be cured by resection. Given the importance of preserving visual function, we analyzed radiological and visual acuity (VA)...
6.
Lamoureux A, Fisher M, Lemelle L, Pfaff E, Amir-Yazdani P, Kramm C, et al.
Clin Cancer Res
. 2024 Dec;
31(3):561-572.
PMID: 39625867
Purpose: Tropomyosin receptor kinase (TRK) fusions are detected in less than 2% of central nervous system tumors. There are limited data on the clinical course of affected patients. Experimental Design:...
7.
Kerras S, Hetherington K, Toofanian S, Manoharan N, Ziegler D, Mateos M
Psychooncology
. 2024 Nov;
33(11):e70011.
PMID: 39558466
Introduction: This study investigated the prevalence, methods and factors leading carers of childhood cancer patients to seek second opinions. Methods: A prospective, questionnaire-based study was conducted among families attending oncology...
8.
Haeusler G, Dashti S, James F, Babl F, Borland M, Clark J, et al.
Lancet Reg Health West Pac
. 2024 Nov;
53:101226.
PMID: 39553416
Background: Prompt antibiotic administration for febrile neutropenia (FN) is standard of care, and targets of time to antibiotics (TTA) <60 min are common. We sought to determine the effect of...
9.
Staunton J, Ajuyah P, Harris A, Mayoh C, Wong M, Rumford M, et al.
NPJ Precis Oncol
. 2024 Oct;
8(1):236.
PMID: 39427038
Noonan Syndrome (NS) is associated with an increased risk of low-grade central nervous system tumours in children but only very rarely associated with high-grade gliomas. Here we describe the first...
10.
Hetherington K, Wakefield C, McGill B, Tucker K, Donoghoe M, Daly R, et al.
Neurooncol Adv
. 2024 Sep;
6(1):vdae133.
PMID: 39220248
Background: Advances in our understanding of the genetic basis of childhood cancer, including primary central nervous system cancers, are improving the diagnosis, treatment, and clinical management of pediatric patients. To...