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Geoff Yu Zhang

Explore the profile of Geoff Yu Zhang including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 234
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Recent Articles
1.
Chung E, Wang Y, Shaw K, Ronning E, Wang Y, Zhang G, et al.
Nephrology (Carlton) . 2025 Feb; 30(2):e70005. PMID: 39970933
Aim: CD8 regulatory T cells (Tregs) are cross-protective across multiple animal models of autoimmunity. Recently, specific peptides from a yeast-peptide-major histocompatibility complex library that expanded CD8 Tregs in murine experimental...
2.
Chung E, Wang Y, Shaw K, Ronning E, Wang Y, Zhang G, et al.
Nephrol Dial Transplant . 2025 Feb; PMID: 39919766
Background And Hypothesis: Recent advances in membranous nephropathy treatment have focused on B cell depletion, which is incompletely effective, potentially due to persistent autoantibody-producing plasma cells or alternative pathways of...
3.
Wang Y, Shaw K, Zhang G, Chung E, Hu M, Cao Q, et al.
J Am Soc Nephrol . 2022 Apr; 33(5):966-984. PMID: 35387873
Background: The cytokine IL-33 is an activator of innate lymphoid cells 2 (ILC2s) in innate immunity and allergic inflammation. B cell activating factor (BAFF) plays a central role in B...
4.
Zhang G, Hu M, Watson D, Wang Y, Knight J, Alexander S
Transplantation . 2020 Feb; 104(7):1385-1395. PMID: 32053573
Background: Tolerance induced in stringent animal transplant models using donor-specific transfusions (DST) has previously required additional immunological manipulation. Here, we demonstrate a dominant skin-allograft tolerance model induced by a single...
5.
Zhou J, Wang Y, Lee V, Zhang G, Medbury H, Williams H, et al.
PLoS One . 2018 Apr; 13(4):e0195657. PMID: 29641559
Studies disrupting the chemokine pathway CX3CL1 (fractalkine)/ CX3CR1 have shown decreased atherosclerosis in animal models but the techniques used to interrupt the pathway have not been easily translatable into human...
6.
Qiao X, Rao P, Zhang Y, Liu L, Pang M, Wang H, et al.
J Am Soc Nephrol . 2017 Nov; 29(2):557-570. PMID: 29180394
TGF- is a key profibrotic factor, but targeting TGF- to prevent fibrosis also abolishes its protective anti-inflammatory effects. Here, we investigated the hypothesis that we can redirect TGF- signaling by...
7.
Wang Y, Ghali J, Zhang G, Hu M, Wang Y, Sawyer A, et al.
Nephrology (Carlton) . 2015 Oct; 21(2):81-5. PMID: 26461175
Regulatory T cells (Tregs) have been recognized as having a major role in maintaining peripheral tolerance and preventing and limiting autoimmune and chronic inflammatory diseases. Tregs derive from the thymus...
8.
Watson D, Zhang G, Hu M, Wang Y, Fletcher J, Sartor M, et al.
Transpl Immunol . 2014 Apr; 30(4):168-77. PMID: 24746800
Adoptive cell therapies involving cell manipulation to achieve tolerance are increasingly being studied in animal models and in human trials. We have demonstrated that the specific removal of allo-stimulated dividing...
9.
Wang Y, Wang Y, Wang Y, Zheng G, Tan T, Lee S, et al.
Int J Clin Exp Pathol . 2014 Jan; 7(1):38-47. PMID: 24427324
Regulatory T cells (Treg) are important for maintaining immune homeostasis. Adoptive transfer of Tregs is protective in renal disease models in both immunocompetent and immunodeficient mice. However the involvement of...
10.
Wang Y, Zhou J, Wang Y, Watson D, Zhang G, Hu M, et al.
Int J Clin Exp Pathol . 2013 Feb; 6(3):326-33. PMID: 23412421
Chronic kidney disease (CKD) is a major cause of death and morbidity in Australia and worldwide. DNA vaccination has been used for targeting foreign antigens to induce immune responses and...