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Stephen I Alexander

Explore the profile of Stephen I Alexander including associated specialties, affiliations and a list of published articles. Areas
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Articles 176
Citations 4495
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Recent Articles
1.
Chung E, Wang Y, Shaw K, Ronning E, Wang Y, Zhang G, et al.
Nephrol Dial Transplant . 2025 Feb; PMID: 39919766
Background And Hypothesis: Recent advances in membranous nephropathy treatment have focused on B cell depletion, which is incompletely effective, potentially due to persistent autoantibody-producing plasma cells or alternative pathways of...
2.
Mallawaarachchi A, McCarthy H, Forbes T, Jayasinghe K, Patel C, Alexander S, et al.
BMC Nephrol . 2025 Feb; 26(1):51. PMID: 39901087
Background: Genetic kidney disease (GKD) significantly affects the community and is responsible for a notable portion of adult kidney disease cases and about half of cases in paediatric patients. It...
3.
Wu J, Guha C, Hughes A, Torrisi L, Craig J, Sinha A, et al.
Am J Kidney Dis . 2024 Aug; 85(1):14-24.e1. PMID: 39127401
Rationale & Objective: Growth failure is a common problem among children with chronic kidney disease (CKD). Reduced height is associated with psychosocial burden, social stigma, and impaired quality of life....
4.
Mallawaarachchi A, Fowles L, Wardrop L, Wood A, OShea R, Biros E, et al.
Clin J Am Soc Nephrol . 2024 Jun; 19(7):887-897. PMID: 38861662
No abstract available.
5.
Zhao Y, Nicholson L, Wang H, Qian Y, Hawthorne W, Jimenez-Vera E, et al.
JCI Insight . 2024 Mar; 9(6). PMID: 38516885
CD4+Foxp3+ regulatory T cells (Tregs) play an essential role in suppressing transplant rejection, but their role within the graft and heterogeneity in tolerance are poorly understood. Here, we compared phenotypic...
6.
Sligar C, Reilly E, Cuthbertson P, Vine K, Bird K, Elhage A, et al.
Clin Transl Immunology . 2024 Mar; 13(3):e1497. PMID: 38495918
Objectives: Donor haematopoietic stem cell transplantation treats leukaemia by inducing graft-versus-leukaemia (GVL) immunity. However, this benefit is often mitigated by graft-versus-host disease (GVHD), which is reduced by post-transplant cyclophosphamide (PTCy)...
7.
Wu S, Feng Y, Song R, Qi Y, Li L, Lu D, et al.
J Am Soc Nephrol . 2024 Feb; 35(5):533-548. PMID: 38332484
No abstract available.
8.
Wu Y, Jayasinghe K, Stark Z, Quinlan C, Patel C, McCarthy H, et al.
Genet Med . 2023 Oct; 26(1):100989. PMID: 37777873
No abstract available.
9.
Cao Q, Wang R, Niu Z, Chen T, Azmi F, Read S, et al.
JHEP Rep . 2023 Sep; 5(10):100837. PMID: 37691688
Background And Aims: Although type 2 innate lymphoid cells (ILC2s) were originally found to be liver-resident lymphocytes, the role and importance of ILC2 in liver injury remains poorly understood. In...
10.
Sligar C, Cuthbertson P, Miles N, Adhikary S, Elhage A, Zhang G, et al.
Immunol Cell Biol . 2023 May; 101(7):639-656. PMID: 37191045
Graft-versus-host disease (GVHD) is a life-threatening complication following donor hematopoietic stem cell transplantation, where donor T cells damage host tissues. This study investigated the effect of tocilizumab (TOC) combined with...