Gennaro Oliva
Overview
Explore the profile of Gennaro Oliva including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
270
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Recent Articles
1.
Gregoretti F, Lucini F, Cesarini E, Oliva G, Lanzuolo C, Antonelli L
Methods Mol Biol
. 2023 May;
2655:147-169.
PMID: 37212995
Polycomb-group (PcG) of proteins are evolutionarily conserved transcription factors necessary for the regulation of gene expression during the development and the safeguard of cell identity in adulthood. In the nucleus,...
2.
Sebestyen E, Marullo F, Lucini F, Petrini C, Bianchi A, Valsoni S, et al.
Nat Commun
. 2020 Dec;
11(1):6274.
PMID: 33293552
Hutchinson-Gilford progeria syndrome is a genetic disease caused by an aberrant form of Lamin A resulting in chromatin structure disruption, in particular by interfering with lamina associated domains. Early molecular...
3.
Fasciani A, DAnnunzio S, Poli V, Fagnocchi L, Beyes S, Michelatti D, et al.
Nat Genet
. 2020 Nov;
52(12):1397-1411.
PMID: 33169020
The genetic elements required to tune gene expression are partitioned in active and repressive nuclear condensates. Chromatin compartments include transcriptional clusters whose dynamic establishment and functioning depend on multivalent interactions...
4.
Gregoretti F, Cortesi A, Oliva G, Bodega B, Antonelli L
Methods Mol Biol
. 2020 Aug;
2157:299-320.
PMID: 32820411
We present an algorithm, and its MATLAB implementation, based on mathematical methods to detect and localize 3D multicolor DNA FISH spots in fluorescence cell image z-stacks. This algorithm provides a...
5.
Shytaj I, Lucic B, Forcato M, Penzo C, Billingsley J, Laketa V, et al.
EMBO J
. 2020 Mar;
39(9):e102209.
PMID: 32157726
HIV-1 persists in a latent form during antiretroviral therapy, mainly in CD4 T cells, thus hampering efforts for a cure. HIV-1 infection is accompanied by metabolic alterations, such as oxidative...
6.
Bianchi A, Mozzetta C, Pegoli G, Lucini F, Valsoni S, Rosti V, et al.
J Clin Invest
. 2020 Jan;
130(5):2408-2421.
PMID: 31999646
Lamin A is a component of the inner nuclear membrane that, together with epigenetic factors, organizes the genome in higher order structures required for transcriptional control. Mutations in the lamin...
7.
Cortesi A, Pesant M, Sinha S, Marasca F, Sala E, Gregoretti F, et al.
Genome Res
. 2019 May;
29(6):883-895.
PMID: 31097473
Despite increasing insights in genome structure organization, the role of DNA repetitive elements, accounting for more than two thirds of the human genome, remains elusive. Facioscapulohumeral muscular dystrophy (FSHD) is...
8.
Gregoretti F, Cesarini E, Lanzuolo C, Oliva G, Antonelli L
Methods Mol Biol
. 2016 Sep;
1480:181-97.
PMID: 27659985
The large amount of data generated in biological experiments that rely on advanced microscopy can be handled only with automated image analysis. Most analyses require a reliable cell image segmentation...
9.
Cesarini E, Mozzetta C, Marullo F, Gregoretti F, Gargiulo A, Columbaro M, et al.
J Cell Biol
. 2015 Nov;
211(3):533-51.
PMID: 26553927
Beyond its role in providing structure to the nuclear envelope, lamin A/C is involved in transcriptional regulation. However, its cross talk with epigenetic factors--and how this cross talk influences physiological...
10.
A community-based resource for automatic exome variant-calling and annotation in Mendelian disorders
Mutarelli M, Marwah V, Rispoli R, Carrella D, Dharmalingam G, Oliva G, et al.
BMC Genomics
. 2014 Aug;
15 Suppl 3:S5.
PMID: 25078076
Background: Mendelian disorders are mostly caused by single mutations in the DNA sequence of a gene, leading to a phenotype with pathologic consequences. Whole Exome Sequencing of patients can be...