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Genaro Barrientos

Explore the profile of Genaro Barrientos including associated specialties, affiliations and a list of published articles. Areas
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Citations 365
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Recent Articles
1.
Guncay T, Concha J, Lobos P, More J, Bruna B, Sansores D, et al.
J Gerontol A Biol Sci Med Sci . 2025 Jan; PMID: 39823270
Postoperative delirium (POD), an acute cognitive dysfunction linked to morbidity and mortality, is characterized by memory impairments and disturbances in consciousness, particularly in patients aged 65 and older. Neuroinflammation and...
2.
Russell-Guzman J, Americo-Da Silva L, Cadagan C, Maturana M, Palomero J, Estrada M, et al.
Free Radic Biol Med . 2024 Jun; 222:187-198. PMID: 38897422
Oxidative stress and the activation of the nucleotide-binding domain, leucine-rich-containing family, pyrin domain containing 3 (NLRP3) inflammasome have been linked to insulin resistance in skeletal muscle. In immune cells, the...
3.
Valdes-Undurraga I, Lobos P, Sanchez-Robledo V, Arias-Cavieres A, SanMartin C, Barrientos G, et al.
Front Cell Neurosci . 2023 Apr; 17:1132121. PMID: 37025696
Neuronal Ca signals generated through the activation of Ca-induced Ca release in response to activity-generated Ca influx play a significant role in hippocampal synaptic plasticity, spatial learning, and memory. We...
4.
Americo-Da-Silva L, Aguilera J, Quinteros-Waltemath O, Sanchez-Aguilera P, Russell J, Cadagan C, et al.
Int J Mol Sci . 2021 Oct; 22(19). PMID: 34638553
Low-grade chronic inflammation plays a pivotal role in the pathogenesis of insulin resistance (IR), and skeletal muscle has a central role in this condition. NLRP3 inflammasome activation pathways promote low-grade...
5.
Basualto-Alarcon C, Llanos P, Garcia-Rivas G, Troncoso M, Lagos D, Barrientos G, et al.
Int J Endocrinol . 2021 Aug; 2021:5527973. PMID: 34335746
In men, 70% of circulating testosterone binds with high affinity to plasma sex hormone binding globulin (SHBG), which determines its bioavailability in their target cells. In recent years, a growing...
6.
Jorquera G, Russell J, Monsalves-Alvarez M, Cruz G, Valladares-Ide D, Basualto-Alarcon C, et al.
Int J Mol Sci . 2021 Apr; 22(6). PMID: 33806797
Among multiple mechanisms, low-grade inflammation is critical for the development of insulin resistance as a feature of type 2 diabetes. The nucleotide-binding oligomerization domain-like receptor family (NOD-like) pyrin domain containing...
7.
Troncoso M, Pavez M, Wilson C, Lagos D, Duran J, Ramos S, et al.
Biol Res . 2021 Feb; 54(1):3. PMID: 33546773
Background: Testosterone regulates nutrient and energy balance to maintain protein synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce cardiac hypertrophy. Previously, we determined that testosterone increased glucose uptake-via AMP-activated...
8.
Barrientos G, Llanos P, Basualto-Alarcon C, Estrada M
Front Endocrinol (Lausanne) . 2020 Jun; 11:316. PMID: 32499759
The prevalence of cardiovascular mortality is higher in men than in age-matched premenopausal women. Gender differences are linked to circulating sex-related steroid hormone levels and their cardio-specific actions, which are...
9.
Murphy M, Qin X, Kaul S, Barrientos G, Zou Z, Mathias C, et al.
Eur J Pharmacol . 2020 Feb; 875:173036. PMID: 32101765
Ellagic acid, a naturally occurring phenol found in a variety of fruits and nuts has been shown to possess anti-inflammatory properties. However, the mechanism of action behind its anti-inflammatory action...
10.
Arias-Cavieres A, More J, Vicente J, Adasme T, Hidalgo J, Valdes J, et al.
Front Mol Neurosci . 2018 Dec; 11:429. PMID: 30534053
Triclosan, a widely used industrial and household agent, is present as an antiseptic ingredient in numerous products of everyday use, such as toothpaste, cosmetics, kitchenware, and toys. Previous studies have...