Manuel Estrada
Overview
Explore the profile of Manuel Estrada including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
887
Followers
0
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Recent Articles
1.
Russell-Guzman J, Americo-Da Silva L, Cadagan C, Maturana M, Palomero J, Estrada M, et al.
Free Radic Biol Med
. 2024 Jun;
222:187-198.
PMID: 38897422
Oxidative stress and the activation of the nucleotide-binding domain, leucine-rich-containing family, pyrin domain containing 3 (NLRP3) inflammasome have been linked to insulin resistance in skeletal muscle. In immune cells, the...
2.
McMahon C, Hurley E, Perez A, Estrada M, Lodge D, Hsieh J
JCI Insight
. 2024 May;
9(13).
PMID: 38781563
Prenatal exposure to viral pathogens has been known to cause the development of neuropsychiatric disorders in adulthood. Furthermore, COVID-19 has been associated with a variety of neurological manifestations, raising the...
3.
Alves-Figueiredo H, Silva-Platas C, Estrada M, Oropeza-Almazan Y, Ramos-Gonzalez M, Bernal-Ramirez J, et al.
JACC Basic Transl Sci
. 2024 Apr;
9(4):496-518.
PMID: 38680963
The role of the mitochondrial calcium uniporter (MCU) in energy dysfunction and hypertrophy in heart failure (HF) remains unknown. In angiotensin II (ANGII)-induced hypertrophic cardiac cells we have shown that...
4.
Sarabia-Vallejos M, Romero De la Fuente S, Tapia P, Cohn-Inostroza N, Estrada M, Ortiz-Puerta D, et al.
Polymers (Basel)
. 2024 Feb;
16(4).
PMID: 38399850
Patients with bone diseases often experience increased bone fragility. When bone injuries exceed the body's natural healing capacity, they become significant obstacles. The global rise in the aging population and...
5.
McMahon C, Castro J, Silvas J, Perez A, Estrada M, Carrion Jr R, et al.
Brain Behav Immun
. 2023 Jun;
112:188-205.
PMID: 37329995
Whether or not SARS-CoV-2 can cross from mother to fetus during a prenatal infection has been controversial; however, recent evidence such as viral RNA detection in umbilical cord blood and...
6.
Americo-Da-Silva L, Aguilera J, Quinteros-Waltemath O, Sanchez-Aguilera P, Russell J, Cadagan C, et al.
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34638553
Low-grade chronic inflammation plays a pivotal role in the pathogenesis of insulin resistance (IR), and skeletal muscle has a central role in this condition. NLRP3 inflammasome activation pathways promote low-grade...
7.
Basualto-Alarcon C, Llanos P, Garcia-Rivas G, Troncoso M, Lagos D, Barrientos G, et al.
Int J Endocrinol
. 2021 Aug;
2021:5527973.
PMID: 34335746
In men, 70% of circulating testosterone binds with high affinity to plasma sex hormone binding globulin (SHBG), which determines its bioavailability in their target cells. In recent years, a growing...
8.
Jorquera G, Russell J, Monsalves-Alvarez M, Cruz G, Valladares-Ide D, Basualto-Alarcon C, et al.
Int J Mol Sci
. 2021 Apr;
22(6).
PMID: 33806797
Among multiple mechanisms, low-grade inflammation is critical for the development of insulin resistance as a feature of type 2 diabetes. The nucleotide-binding oligomerization domain-like receptor family (NOD-like) pyrin domain containing...
9.
Duran J, Nickel L, Estrada M, Backs J, van den Hoogenhof M
Front Cell Dev Biol
. 2021 Mar;
9:644630.
PMID: 33777949
RNA splicing has been recognized in recent years as a pivotal player in heart development and disease. The Ca/calmodulin dependent protein kinase II delta (CaMKIIδ) is a multifunctional Ser/Thr kinase...
10.
Troncoso M, Pavez M, Wilson C, Lagos D, Duran J, Ramos S, et al.
Biol Res
. 2021 Feb;
54(1):3.
PMID: 33546773
Background: Testosterone regulates nutrient and energy balance to maintain protein synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce cardiac hypertrophy. Previously, we determined that testosterone increased glucose uptake-via AMP-activated...