Gen Nishikawa
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Explore the profile of Gen Nishikawa including associated specialties, affiliations and a list of published articles.
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10
Citations
195
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Recent Articles
1.
Nakano Y, Nishikawa G, Degawa K, Moriyoshi K, Kuriyama K, Watanabe Y, et al.
Clin J Gastroenterol
. 2025 Mar;
PMID: 40029573
A 90-year-old man underwent a colonoscopy due to abdominal distension, revealing half-circumferential Type 2 advanced cancers in the ascending and transverse colon. No distant metastasis was detected, and 3 months...
2.
Narita M, Moriyoshi K, Yamaoka R, Moriyama M, Degawa K, Fushitani M, et al.
Langenbecks Arch Surg
. 2023 Nov;
408(1):431.
PMID: 37940752
Purpose: Preoperative pain is known as one of the most powerful risk factors for chronic postoperative inguinal pain (CPIP), while its pathogenesis has not been fully elucidated. The aim of...
3.
Hu B, Toda K, Wang X, Antczak M, Smith J, Geboers S, et al.
J Med Chem
. 2022 Nov;
65(22):15327-15343.
PMID: 36322935
15-Prostaglandin dehydrogenase (15-PGDH) regulates the concentration of prostaglandin E2 . Inhibitors of 15-PGDH elevate PGE2 levels and promote tissue repair and regeneration. Here, we describe a novel class of quinoxaline...
4.
Nishikawa G, Kawada K, Hanada K, Maekawa H, Itatani Y, Miyoshi H, et al.
Cells
. 2022 Oct;
11(20).
PMID: 36291140
Reprogramming of energy metabolism is regarded as one of the hallmarks of cancer; in particular, oncogenic RAS has been shown to be a critical regulator of cancer metabolism. Recently, asparagine...
5.
Hanada K, Kawada K, Nishikawa G, Toda K, Maekawa H, Nishikawa Y, et al.
Cancer Lett
. 2021 Sep;
522:129-141.
PMID: 34543685
Mutations of KRAS gene are found in various types of cancer, including colorectal cancer (CRC). Despite intense efforts, no pharmacological approaches are expected to be effective against KRAS-mutant cancers. Macropinocytosis...
6.
Kiyasu Y, Kawada K, Hirai H, Ogawa R, Hanada K, Masui H, et al.
Cancer Lett
. 2020 May;
487:53-62.
PMID: 32473241
Tumor-stromal interaction is implicated in tumor progression. Although CCR1 expression in myeloid cells could be associated with pro-tumor activity, it remains elusive whether disruption of CCR1-mediated myeloid cell accumulation can...
7.
Nishikawa G, Kawada K, Nakagawa J, Toda K, Ogawa R, Inamoto S, et al.
Cell Death Dis
. 2019 Mar;
10(4):264.
PMID: 30890699
Mesenchymal stem cells (MSCs) are recruited from BM to the stroma of developing tumors, where they serve as critical components of the tumor microenvironment by secreting growth factors, cytokines, and...
8.
Ogawa R, Yamamoto T, Hirai H, Hanada K, Kiyasu Y, Nishikawa G, et al.
Clin Cancer Res
. 2019 Feb;
25(9):2887-2899.
PMID: 30705034
Purpose: SMAD4 is a key transcriptional factor of TGFβ signaling and acts as a tumor suppressor in colorectal cancer. In the present study, we explored the immunologic effect of SMAD4...
9.
Toda K, Nishikawa G, Iwamoto M, Itatani Y, Takahashi R, Sakai Y, et al.
Int J Mol Sci
. 2017 Jul;
18(8).
PMID: 28749408
Mutation in the gene induces prominent metabolic changes. We have recently reported that mutations in colorectal cancer (CRC) cause alterations in amino acid metabolism. However, it remains to be investigated...
10.
Nishikawa G, Minamiguchi S, Hata H, Ogiso S, Yamaguchi T, Otani T, et al.
Int Surg
. 2015 Jan;
100(1):128-32.
PMID: 25594652
We present a rare case of dedifferentiated liposarcoma confined to the spleen and splenic hilum. An 81-year-old man was referred to our hospital with a large asymptomatic splenic tumor. The...