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Ge Hong

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Articles 27
Citations 196
Followers 0
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Recent Articles
1.
Zhu N, Meng S, Mao L, Rong Y, Wang X, Liu Y, et al.
Bioorg Chem . 2024 Sep; 153:107824. PMID: 39305608
Abiraterone (Abi), an effective cytochrome oxidase P450 C17 (CYP17) inhibitor, inhibits androgen synthesis in testes, adrenal glands, and prostate tumors. However, their low bioavailability and dissolution rate due to their...
2.
Guo N, Chen J, Kong F, Gao Y, Bian J, Liu T, et al.
Biomed Pharmacother . 2024 Jul; 178:117132. PMID: 39047418
Recent research indicated that ulcers and peripheral vascular disease resulting from drug-resistant bacterial infections are the main causes of delayed healing in chronic diabetic wounds. 5-Aminolevulinic acid (ALA) is a...
3.
Ji H, Dong T, Liang G, Xu H, Wang C, Liu T, et al.
Photodiagnosis Photodyn Ther . 2023 Oct; 44:103857. PMID: 37890810
Background: Pseudomonas aeruginosa is a gram-negative bacterium without spores, and it is one of the pathogens that easily cause secondary infectious diseases when human immune function is low. The purpose...
4.
Liu Y, Hong G, Mao L, Su Z, Liu T, Liu H
Molecules . 2023 May; 28(9). PMID: 37175072
Paclitaxel-triethylenetetramine hexaacetic acid conjugate (PTX-TTHA), a novel semi-synthetic taxane, is designed to improve the water solubility and cosolvent toxicity of paclitaxel in several aminopolycarboxylic acid groups. In this study, the...
5.
Hong G, Li W, Mao L, Wang J, Liu T
Front Chem . 2022 Sep; 10:963442. PMID: 36059868
A series of small-molecule fluoroquinolones were synthesized, characterized by HRMS and NMR spectroscopy, and screened for their antibacterial activity against MRSA, , and as model G/G pathogens. Compounds , ,...
6.
Ma S, Zhang N, Hou J, Liu S, Wang J, Lu B, et al.
Front Chem . 2022 Aug; 10:941367. PMID: 35958230
Ligustrazine (TMP) is a natural pyrazine alkaloid extracted from the roots of Ligusticum Chuanxiong Hort, which has the potential as an antitumor agent. A series of 33 ligustrazine-heterocycle (TMPH) derivatives...
7.
Wang L, Huang S, Zhu T, Ge X, Pei C, Hong G, et al.
Chem Res Toxicol . 2022 Jan; 35(2):244-253. PMID: 35081708
Iohexol, the raw material of nonionic X-ray computed tomography (X-CT) contrast medium, is usually injected into the vein before CT angiography diagnosis. It is used for angiography, urography, and lymphography....
8.
Rong Y, Hong G, Zhu N, Liu Y, Jiang Y, Liu T
Front Pharmacol . 2021 Nov; 12:746725. PMID: 34744725
Ulcerative colitis (UC), a chronic, nonspecific inflammatory bowel disease characterized by continuous and diffuse inflammatory changes in the colonic mucosa, requires novel treatment method. Photodynamic therapy (PDT), as a promising...
9.
Wang W, Wang J, Hong G, Mao L, Zhu N, Liu T
Biomacromolecules . 2021 Sep; 22(10):4284-4294. PMID: 34569232
Highly tumor-tissue-selective drugs are a prerequisite for accurate diagnosis and efficient photodynamic therapy (PDT) of tumors, but the currently used fluorescent dyes and photosensitizers generally lack the ability for high...
10.
Huang S, Tang Y, Liu T, Zhang N, Yang X, Yang D, et al.
Front Pharmacol . 2021 Jul; 12:724416. PMID: 34305622
[This corrects the article DOI: 10.3389/fphar.2020.599577.].