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Gayle P Pouliot

Explore the profile of Gayle P Pouliot including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 133
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Recent Articles
1.
Hamilton E, Wang J, Oza A, Patel M, Ulahannan S, Bauer T, et al.
Mol Cancer Ther . 2023 Jul; 22(10):1154-1165. PMID: 37486983
AZD5153, a reversible, bivalent inhibitor of the bromodomain and extraterminal family protein BRD4, has preclinical activity in multiple tumors. This first-in-human, phase I study investigated AZD5153 alone or with olaparib...
2.
Lim E, Bendell J, Falchook G, Bauer T, Drake C, Choe J, et al.
Clin Cancer Res . 2022 Aug; 28(22):4871-4884. PMID: 36044531
Purpose: To evaluate AZD4635, an adenosine A2A receptor antagonist, as monotherapy or in combination with durvalumab in patients with advanced solid tumors. Patients And Methods: In phase Ia (dose escalation),...
3.
Pouliot G, Degar J, Hinze L, Kochupurakkal B, Vo C, Burns M, et al.
PLoS One . 2019 Nov; 14(11):e0221288. PMID: 31721781
BRCA2 (also known as FANCD1) is a core component of the Fanconi pathway and suppresses transformation of immature T-cells in mice. However, the contribution of Fanconi-BRCA pathway deficiency to human...
4.
Burns M, Liao Z, Yamagata N, Pouliot G, Stevenson K, Neuberg D, et al.
Leukemia . 2018 Apr; 32(10):2126-2137. PMID: 29654263
The role of Hedgehog signaling in normal and malignant T-cell development is controversial. Recently, Hedgehog pathway mutations have been described in T-ALL, but whether mutational activation of Hedgehog signaling drives...
5.
Hall L, Byron M, Carone D, Whitfield T, Pouliot G, Fischer A, et al.
Cell Rep . 2017 Mar; 18(12):2943-2956. PMID: 28329686
This study reveals that high-copy satellite II (HSATII) sequences in the human genome can bind and impact distribution of chromatin regulatory proteins and that this goes awry in cancer. In...
6.
Pouliot G, Gutierrez A
Nat Med . 2014 Oct; 20(10):1096-7. PMID: 25295936
No abstract available.