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Kristen E Stevenson

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Articles 70
Citations 3452
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Recent Articles
1.
Winter P, Ramseier M, Navia A, Saksena S, Strouf H, Senhaji N, et al.
bioRxiv . 2024 Jun; PMID: 38915726
Efforts to cure BCR::ABL1 B cell acute lymphoblastic leukemia (Ph+ ALL) solely through inhibition of ABL1 kinase activity have thus far been insufficient despite the availability of tyrosine kinase inhibitors...
2.
Lane A, Garcia J, Raulston E, Garzon J, Galinsky I, Baxter E, et al.
Blood Adv . 2023 Dec; 8(3):591-602. PMID: 38052038
CD123, a subunit of the interleukin-3 receptor, is expressed on ∼80% of acute myeloid leukemias (AMLs). Tagraxofusp (TAG), recombinant interleukin-3 fused to a truncated diphtheria toxin payload, is a first-in-class...
3.
Wu G, Yoshida N, Liu J, Zhang X, Xiong Y, Heavican-Foral T, et al.
Sci Transl Med . 2023 Sep; 15(714):eadi7244. PMID: 37729434
Gene fusions involving tumor protein p63 gene (TP63) occur in multiple T and B cell lymphomas and portend a dismal prognosis for patients. The function and mechanisms of TP63 fusions...
4.
Welch J, Flamand Y, Stevenson K, Neuberg D, Athale U, Kelly K, et al.
Pediatr Blood Cancer . 2023 Jul; 70(11):e30560. PMID: 37461125
Background: Children treated for acute lymphoblastic leukemia (ALL) receive prolonged treatment, resulting in toxicities that affect health-related quality of life (HR-QoL). Longitudinal assessment of HR-QoL allows improved understanding of experiences...
5.
Arwood M, Liu Y, Harkins S, Weinstock D, Yang L, Stevenson K, et al.
Cell Chem Biol . 2023 Jun; 30(6):618-631.e12. PMID: 37290440
Recurrent JAK2 alterations are observed in myeloproliferative neoplasms, B-cell acute lymphoblastic leukemia, and other hematologic malignancies. Currently available type I JAK2 inhibitors have limited activity in these diseases. Preclinical data...
6.
Raman H, Kim S, DeAngelo D, Stevenson K, Neuberg D, Winer E, et al.
Leuk Res . 2022 Dec; 125:107004. PMID: 36577290
Tyrosine kinase inhibitors (TKIs) are essential for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) and have allowed for effective, low intensity induction regimens including no or minimal...
7.
Knisbacher B, Lin Z, Hahn C, Nadeu F, Duran-Ferrer M, Stevenson K, et al.
Nat Genet . 2022 Aug; 54(11):1664-1674. PMID: 35927489
Recent advances in cancer characterization have consistently revealed marked heterogeneity, impeding the completion of integrated molecular and clinical maps for each malignancy. Here, we focus on chronic lymphocytic leukemia (CLL),...
8.
Valtis Y, Stevenson K, Murphy E, Hong J, Ali M, Shah S, et al.
J Gen Intern Med . 2022 May; 38(1):30-35. PMID: 35556213
Background: Security emergency responses (SERs) are utilized by hospitals to ensure the safety of patients and staff but can cause unintended morbidity. The presence of racial and ethnic inequities in...
9.
Bodaar K, Yamagata N, Barthe A, Landrigan J, Chonghaile T, Burns M, et al.
Leukemia . 2022 Apr; 36(6):1499-1507. PMID: 35411095
Resistance to mitochondrial apoptosis predicts inferior treatment outcomes in patients with diverse tumor types, including T-cell acute lymphoblastic leukemia (T-ALL). However, the genetic basis for variability in this mitochondrial apoptotic...
10.
Athale U, Flamand Y, Blonquist T, Stevenson K, Spira M, Asselin B, et al.
Pediatr Blood Cancer . 2022 Mar; 69(8):e29581. PMID: 35316569
Background/objectives: Although thromboembolism (TE) is a serious complication in patients with acute lymphoblastic leukemia (ALL), thromboprophylaxis is not commonly used due to the inherent bleeding risk in this population. Identifying...