Gavin W G Wilkinson
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Explore the profile of Gavin W G Wilkinson including associated specialties, affiliations and a list of published articles.
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54
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3037
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Recent Articles
1.
Vlachava V, Seirafian S, Fielding C, Kollnberger S, Aicheler R, Hughes J, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(49):e2309077120.
PMID: 38011551
Human cytomegalovirus (HCMV) is a paradigm of pathogen immune evasion and sustains lifelong persistent infection in the face of exceptionally powerful host immune responses through the concerted action of multiple...
2.
Rubina A, Patel M, Nightingale K, Potts M, Fielding C, Kollnberger S, et al.
Proc Natl Acad Sci U S A
. 2023 Aug;
120(33):e2303155120.
PMID: 37561786
Human cytomegalovirus (HCMV) is a major human pathogen whose life-long persistence is enabled by its remarkable capacity to systematically subvert host immune defenses. In exploring the finding that HCMV infection...
3.
Elasifer H, Wang E, Prodhomme V, Davies J, Forbes S, Stanton R, et al.
J Gen Virol
. 2020 Jun;
101(8):863-872.
PMID: 32510303
Molluscum contagiosum virus (MCV) is a common cause of benign skin lesions in young children and currently the only endemic human poxvirus. Following the infection of primary keratinocytes in the...
4.
Suarez N, Wilkie G, Hage E, Camiolo S, Holton M, Hughes J, et al.
J Infect Dis
. 2019 May;
220(5):781-791.
PMID: 31050742
The genomic characteristics of human cytomegalovirus (HCMV) strains sequenced directly from clinical pathology samples were investigated, focusing on variation, multiple-strain infection, recombination, and gene loss. A total of 207 datasets...
5.
Nightingale K, Lin K, Ravenhill B, Davies C, Nobre L, Fielding C, et al.
Cell Host Microbe
. 2018 Aug;
24(3):447-460.e11.
PMID: 30122656
Human cytomegalovirus (HCMV) is an important pathogen with multiple immune evasion strategies, including virally facilitated degradation of host antiviral restriction factors. Here, we describe a multiplexed approach to discover proteins...
6.
Wang E, Pjechova M, Nightingale K, Vlahava V, Patel M, Ruckova E, et al.
Proc Natl Acad Sci U S A
. 2018 Apr;
115(19):4998-5003.
PMID: 29691324
CD58 is an adhesion molecule that is known to play a critical role in costimulation of effector cells and is intrinsic to immune synapse structure. Herein, we describe a virally...
7.
Murrell I, Bedford C, Ladell K, Miners K, Price D, Tomasec P, et al.
Proc Natl Acad Sci U S A
. 2017 May;
114(23):6104-6109.
PMID: 28533400
Human cytomegalovirus (HCMV) strains that have been passaged in vitro rapidly acquire mutations that impact viral growth. These laboratory-adapted strains of HCMV generally exhibit restricted tropism, produce high levels of...
8.
Suarez N, Lau B, Kemble G, Lee R, Mocarski E, Wilkinson G, et al.
Virus Genes
. 2017 Apr;
53(4):650-655.
PMID: 28391502
Human cytomegalovirus (HCMV) is an important opportunistic pathogen in immunocompromised patients and a major cause of congenital birth defects when acquired in utero. In the 1990s, four chimeric viruses were...
9.
Fielding C, Weekes M, Nobre L, Ruckova E, Wilkie G, Paulo J, et al.
Elife
. 2017 Feb;
6.
PMID: 28186488
The human cytomegalovirus (HCMV) US12 family consists of ten sequentially arranged genes (US12-21) with poorly characterized function. We now identify novel natural killer (NK) cell evasion functions for four members:...
10.
Murrell I, Wilkie G, Davison A, Statkute E, Fielding C, Tomasec P, et al.
J Virol
. 2016 Feb;
90(8):3929-43.
PMID: 26842472
Unlabelled: Clinical human cytomegalovirus (HCMV) strains invariably mutate when propagatedin vitro Mutations in gene RL13 are selected in all cell types, whereas in fibroblasts mutants in the UL128 locus (UL128L;...