Gavin Sampey
Overview
Explore the profile of Gavin Sampey including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
600
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0
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Recent Articles
1.
Falcinelli S, Peterson J, Turner A, Irlbeck D, Read J, Raines S, et al.
J Clin Invest
. 2022 Apr;
132(8).
PMID: 35426377
Latency reversal strategies for HIV cure using inhibitor of apoptosis protein (IAP) antagonists (IAPi) induce unprecedented levels of latent reservoir expression without immunotoxicity during suppressive antiretroviral therapy (ART). However, full...
2.
Akpamagbo Y, DeMarino C, Pleet M, Schwab A, Rodriguez M, Barclay R, et al.
Curr Pharm Des
. 2017 Jun;
23(28):4133-4144.
PMID: 28641535
Background: HIV-1 can be preserved in long-lived resting CD4+ T- and myeloid cells, forming a viral reservoir in tissues of the infected individuals. Infected patients primarily receive cART, which, to...
3.
Jaworski E, Saifuddin M, Sampey G, Shafagati N, Van Duyne R, Iordanskiy S, et al.
PLoS One
. 2014 May;
9(5):e96778.
PMID: 24820173
HIV-1 infection results in a chronic but incurable illness since long-term HAART can keep the virus to an undetectable level. However, discontinuation of therapy rapidly increases viral burden. Moreover, patients...
4.
Amaya M, Voss K, Sampey G, Senina S, de la Fuente C, Mueller C, et al.
PLoS One
. 2014 Mar;
9(2):e86745.
PMID: 24586253
Venezuelan equine encephalitis virus (VEEV) belongs to the genus Alphavirus, family Togaviridae. VEEV infection is characterized by extensive inflammation and studies from other laboratories implicated an involvement of the NF-κB...
5.
Fleming A, Sampey G, Chung M, Bailey C, van Hoek M, Kashanchi F, et al.
Pathog Dis
. 2014 Jan;
71(2):109-20.
PMID: 24449527
Exosomes have recently been classified as the newest family members of 'bioactive vesicles' that function to promote intercellular communication. Long ignored and thought to be only a mechanism by which...
6.
Narayanan A, Amaya M, Voss K, Chung M, Benedict A, Sampey G, et al.
Virology
. 2014 Jan;
449:270-86.
PMID: 24418562
Rift Valley fever virus (RVFV) infection is often associated with pronounced liver damage. Previously, our studies revealed altered host phospho-signaling responses (NFκB, MAPK and DNA damage responses) in RVFV infected...
7.
Narayanan A, Iordanskiy S, Das R, Van Duyne R, Santos S, Jaworski E, et al.
J Biol Chem
. 2013 May;
288(27):20014-33.
PMID: 23661700
Exosomes are nano-sized vesicles produced by healthy and virus-infected cells. Exosomes derived from infected cells have been shown to contain viral microRNAs (miRNAs). HIV-1 encodes its own miRNAs that regulate...
8.
Van Duyne R, Guendel I, Jaworski E, Sampey G, Klase Z, Chen H, et al.
J Mol Biol
. 2012 Dec;
425(4):812-29.
PMID: 23247501
Potent anti-retroviral therapy has transformed HIV-1 infection into a chronic manageable disease; however, drug resistance remains a common problem that limits the effectiveness and clinical benefits of this type of...
9.
Currer R, Van Duyne R, Jaworski E, Guendel I, Sampey G, Das R, et al.
Front Microbiol
. 2012 Dec;
3:406.
PMID: 23226145
Human T-cell lymphotropic virus type 1 (HTLV-1) has been identified as the causative agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The virus infects between 15...
10.
Narayanan A, Sampey G, Van Duyne R, Guendel I, Kehn-Hall K, Roman J, et al.
Virology
. 2012 Jul;
432(1):219-31.
PMID: 22771113
Human immunodeficiency virus type 1 (HIV-1) is the etiological agent of AIDS. Chronic persistent infection is an important reason for the presence of "latent cell populations" even after Anti-Retroviral Therapy...