Gavin P Robertson
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Explore the profile of Gavin P Robertson including associated specialties, affiliations and a list of published articles.
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107
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3674
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Recent Articles
1.
Zhang F, Cheng D, Porter K, Heck E, Wang S, Zhang H, et al.
Nat Commun
. 2025 Feb;
16(1):1211.
PMID: 39905075
Telomeres shorten with each cell division, serving as biomarkers of aging, with human tissues exhibiting short telomeres and restricted telomerase expression. In contrast, mice have longer telomeres and widespread telomerase...
2.
Vangala V, Chen Y, Dinavahi S, Gowda K, Lone N, Herlyn M, et al.
ACS Pharmacol Transl Sci
. 2024 Nov;
7(11):3573-3584.
PMID: 39539277
The goal of this project was to demonstrate that subpopulations of cells in tumors can uniquely fluctuate in size in response to environmental conditions created during drug treatment, thereby acting...
3.
Chen Y, Bazewicz C, Dinavahi S, Huntington N, Schell T, Robertson G
Mol Cancer Ther
. 2024 Oct;
PMID: 39470047
The p53 pathway plays an important role in role in cancer immunity. Mutation or downregulation of the proteins in the p53 pathway are prevalent in many cancers, contributing to tumor...
4.
Gowda K, Raza A, Vangala V, Lone N, Lin J, Singh J, et al.
Molecules
. 2024 Jul;
29(13).
PMID: 38999066
Aldehyde dehydrogenases (ALDHs) are a family of enzymes that aid in detoxification and are overexpressed in several different malignancies. There is a correlation between increased expression of ALDH and a...
5.
Chen Y, Gowda K, Amin S, Schell T, Sharma A, Robertson G
Pharmacol Res
. 2024 Apr;
203():107163.
PMID: 38569982
Current cancer therapy can be effective, but the development of drug resistant disease is the usual outcome. These drugs can eliminate most of the tumor burden but often fail to...
6.
Cheng D, Zhang F, Porter K, Wang S, Zhang H, Davis C, et al.
Res Sq
. 2024 Jan;
PMID: 38260456
Telomeres undergo shortening with each cell division, serving as biomarkers of human aging, which is characterized by short telomeres and restricted telomerase expression in adult tissues. Contrarily, mice, featuring their...
7.
Zhang J, Zhang F, Porter K, Dakup P, Wang S, Robertson G, et al.
Int J Cancer
. 2023 Sep;
154(3):548-560.
PMID: 37727982
Telomerase activation is a crucial step in melanomagenesis, often occurring because of ultraviolet radiation (UVR)-induced mutations at the telomerase gene (TERT) promoter and rendering TERT transcription in response to the...
8.
Elbezanti W, Al-Odat O, Chitren R, Singh J, Srivastava S, Gowda K, et al.
Front Pharmacol
. 2022 Sep;
13:894535.
PMID: 36160379
Despite recent improvements in multiple myeloma (MM) treatment, MM remains an incurable disease and most patients experience a relapse. The major reason for myeloma recurrence is the persistent stem cell-like...
9.
Dhanyamraju P, Schell T, Amin S, Robertson G
Cancer Res
. 2022 May;
82(14):2503-2514.
PMID: 35584245
One of the current stumbling blocks in our fight against cancer is the development of acquired resistance to therapy, which is attributable to approximately 90% of cancer-related deaths. Undercutting this...
10.
Dinavahi S, Chen Y, Punnath K, Berg A, Herlyn M, Foroutan M, et al.
Cancer Immunol Res
. 2022 Apr;
10(6):757-769.
PMID: 35439317
Immunotherapy has revolutionized cancer treatment. Unfortunately, most tumor types do not respond to immunotherapy due to a lack of immune infiltration or "cold" tumor microenvironment (TME), a contributing factor in...