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Gavin M Douglas

Explore the profile of Gavin M Douglas including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 11723
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Recent Articles
1.
Douglas G, Shapiro B
Nat Ecol Evol . 2024 Jan; 8(2):304-314. PMID: 38177690
A long-standing question is to what degree genetic drift and selection drive the divergence in rare accessory gene content between closely related bacteria. Rare genes, including singletons, make up a...
2.
El Chaar M, Khoury Y, Douglas G, El Kazzi S, Jisr T, Soussi S, et al.
Microbiol Spectr . 2024 Jan; 12(2):e0312823. PMID: 38171007
Colonization with multidrug-resistant strains causes a substantial health burden in hospitalized patients. We performed a longitudinal genomics study to investigate the colonization of resistant strains in critically ill patients and...
3.
Douglas G, Kim S, Langille M, Shapiro B
Bioinformatics . 2022 Dec; 39(1). PMID: 36519836
Motivation: Microbiome datasets with taxa linked to the functions (e.g. genes) they encode are becoming more common as metagenomics sequencing approaches improve. However, these data are challenging to analyze due...
4.
Douglas G, Hayes M, Langille M, Borenstein E
Bioinformatics . 2022 Sep; 38(22):5055-5063. PMID: 36179077
Motivation: Microbiome functional data are frequently analyzed to identify associations between microbial functions (e.g. genes) and sample groups of interest. However, it is challenging to distinguish between different possible explanations...
5.
Migicovsky Z, Douglas G, Myles S
Front Genet . 2022 Sep; 13:934712. PMID: 36092877
No abstract available.
6.
Nearing J, Douglas G, Hayes M, MacDonald J, Desai D, Allward N, et al.
Nat Commun . 2022 Feb; 13(1):777. PMID: 35115546
No abstract available.
7.
Nearing J, Douglas G, Hayes M, MacDonald J, Desai D, Allward N, et al.
Nat Commun . 2022 Jan; 13(1):342. PMID: 35039521
Identifying differentially abundant microbes is a common goal of microbiome studies. Multiple methods are used interchangeably for this purpose in the literature. Yet, there are few large-scale studies systematically exploring...
8.
Douglas G, Shapiro B
Genome Biol Evol . 2021 Oct; 13(11). PMID: 34665261
Understanding the evolutionary forces shaping prokaryotic pangenome structure is a major goal of microbial evolution research. Recent work has highlighted that a substantial proportion of accessory genes appear to confer...
9.
Cook J, Douglas G, Zhang J, Glick B, Langille M, Liu K, et al.
Innate Immun . 2020 Dec; 27(2):143-157. PMID: 33353474
is an opportunistic bacterial pathogen of plants. Unlike the well-characterized plant defense responses to highly adapted bacterial phytopathogens, little is known about plant response to infection. In this study, we...
10.
Douglas G, Bielawski J, Langille M
Microbiome . 2020 Jun; 8(1):87. PMID: 32513310
Human genome-wide association studies (GWASs) have recurrently estimated lower heritability estimates than familial studies. Many explanations have been suggested to explain these lower estimates, including that a substantial proportion of...