Gauri Shetye
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Explore the profile of Gauri Shetye including associated specialties, affiliations and a list of published articles.
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23
Citations
120
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Recent Articles
1.
Kumar B, Talamadla M, Kumar T, Nandikolla A, Khetmalis Y, Shetye G, et al.
Bioorg Med Chem Lett
. 2025 Mar;
121:130177.
PMID: 40058415
In this work, novel 2-substituted-3-((1-substituted-1H-1,2,3-triazol-4-yl) methoxy) quinoxaline analogues were designed, synthesized, and various analytical techniques, viz., H NMR, C NMR, and Mass spectrometry, were deployed in the structure confirmation of...
2.
Su C, Tuan N, Li W, Cheng J, Jin Y, Hong S, et al.
Synth Syst Biotechnol
. 2025 Feb;
10(2):421-432.
PMID: 39925944
sp. MJM3502 is a promising producer of rufomycins, which are a class of potent anti-tuberculosis lead compounds. Although the structure, activity, and mechanism of the main rufomycin 4/6 and its...
3.
Tan J, Augustinovic M, Omar A, Lourenzon V, Krull N, Lopez X, et al.
ACS Omega
. 2024 Nov;
9(44):44749-44759.
PMID: 39524626
We established a university-community partnership with the Boys and Girls Clubs of Chicago (BGCC)-named b-to involve middle school students in antibiotic discovery research. In the course of working with a...
4.
Wang W, Lee J, Roh E, Shetye G, Cao J, McAlpine J, et al.
J Nat Prod
. 2024 Mar;
87(4):976-983.
PMID: 38438310
Three unique linear oligomeric depsipeptides, designated as cavomycins A-C (-), were identified from , a gut bacterium associated with the annelid . The structures of these depsipeptides were determined through...
5.
Gurgul A, Wu Z, Han K, Shetye G, Sydara K, Souliya O, et al.
Phytochemistry
. 2023 Oct;
216:113884.
PMID: 37813133
Six undescribed compounds, uvarirufols D and E, (+)-uvarigranol B, (-)-uvarigranol E, 6-acetoxy-5-hydroxy-7-methoxyflavanone and cherrevenaphthalene D, along with twelve known compounds, including polyoxygenated cyclohexenes, flavonoids, and lignans, were isolated from the...
6.
Nandikolla A, Khetmalis Y, Kumar B, Chandu A, Karan Kumar B, Shetye G, et al.
RSC Med Chem
. 2023 Aug;
14(8):1549-1561.
PMID: 37593576
The phenanthridine core exhibits antitubercular activity, according to reports from the literature. Several 1,2,3-triazole-based heterocyclic compounds are well-known antitubercular agents. A series of twenty-five phenanthridine amide and 1,2,3-triazole derivatives are...
7.
Lee J, Ma R, Nguyen L, Khan S, Qader M, Mpofu E, et al.
ACS Infect Dis
. 2023 Jul;
9(8):1593-1601.
PMID: 37450563
For over a century, researchers have cultured microorganisms together on solid support─typically agar─in order to observe growth inhibition via antibiotic production. These simple bioassays have been critical to both academic...
8.
Hong J, Duc N, Jeong B, Cho S, Shetye G, Cao J, et al.
Tuberculosis (Edinb)
. 2022 Dec;
138:102298.
PMID: 36580851
Ecumicin and rufomycin 4-7 disrupt protein homeostasis in Mycobacterium tuberculosis by inhibiting the proteolytic activity of the ClpC1/ClpP1/ClpP2 complex. Although these compounds target ClpC1, their effects on the ATPase activity...
9.
Kamat V, Poojary B, Puthran D, Das V, Kumar B, Sankaranarayan M, et al.
Arch Pharm (Weinheim)
. 2022 Dec;
356(3):e2200444.
PMID: 36461683
In the present investigation, we devolved and synthesized a new series of pyrazole-embedded thiazolidin-4-one derivatives (9a-p) with the goal to produce promising antitubercular leads. The in vitro antimycobacterial activity of...
10.
Zhou B, Shetye G, Wolf N, Chen S, Qader M, Ray G, et al.
Org Lett
. 2022 Oct;
24(40):7265-7270.
PMID: 36194676
Four new rufomycins, compounds -, named rufomycins 56, 57, 58, and 61, respectively, exhibiting new skeletal features, were obtained from strain MJM3502 and were fully characterized. Compounds and possess a...