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Gary W Liu

Explore the profile of Gary W Liu including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 104
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Recent Articles
1.
Jimenez M, LHeureux J, Kolaya E, Liu G, Martin K, Ellis H, et al.
Nat Mater . 2024 Jul; 23(10):1436-1443. PMID: 38969782
Microorganisms typically used to produce food and pharmaceuticals are now being explored as medicines and agricultural supplements. However, maintaining high viability from manufacturing until use remains an important challenge, requiring...
2.
Liu G, Pickett M, Kuosmanen J, Ishida K, Madani W, White G, et al.
Nat Mater . 2024 Feb; 23(9):1292-1299. PMID: 38413810
Pills are a cornerstone of medicine but can be challenging to swallow. While liquid formulations are easier to ingest, they lack the capacity to localize therapeutics with excipients nor act...
3.
Liu G, Guzman E, Menon N, Langer R
Pharm Res . 2023 Feb; 40(1):3-25. PMID: 36735106
Endothelial cells play critical roles in circulatory homeostasis and are also the gateway to the major organs of the body. Dysfunction, injury, and gene expression profiles of these cells can...
4.
Liu G, Pippin J, Eng D, Lv S, Shankland S, Pun S
Physiol Rep . 2020 Aug; 8(15):e14545. PMID: 32786069
Loss and dysfunction of glomerular podocytes result in increased macromolecule permeability through the glomerular filtration barrier and nephrotic syndrome. Current therapies can induce and maintain disease remission, but cause serious...
5.
Liu G, Johnson S, Jain R, Peeler D, Shankland S, Pun S
J Biomed Mater Res A . 2019 Aug; 107(12):2718-2725. PMID: 31404486
Progressive loss of glomerular podocytes during kidney disease leads to irreversible kidney failure, and is exacerbated by the fact that podocytes are terminally differentiated epithelial cells and unable to proliferate....
6.
Cheng Y, Liu G, Jain R, Pippin J, Shankland S, Pun S
ACS Biomater Sci Eng . 2019 Jul; 4(12):3968-3973. PMID: 31259236
We report an acid-reversible linker for triggered release of Bis-T-23, an experimental small molecule drug for kidney disease treatment that restores podocyte morphology during disease. Bis-T-23 contains catechols, which form...
7.
Liu G, Prossnitz A, Eng D, Cheng Y, Subrahmanyam N, Pippin J, et al.
Biomaterials . 2018 Jun; 178:317-325. PMID: 29891232
Polymeric drug carriers can alter the pharmacokinetics of their drug cargoes, thereby improving drug therapeutic index and reducing side effects. Understanding and controlling polymer properties that drive tissue-specific accumulation is...
8.
Jing P, Wu J, Liu G, Keeler E, Pun S, Lin L
Sci Rep . 2016 Jan; 6:19924. PMID: 26814808
We propose and demonstrate a new optical trapping method for single cells that utilizes modulated light fields to trap a wide array of cell types, including mammalian, yeast, and Escherichia...
9.
Liu G, Livesay B, Kacherovsky N, Cieslewicz M, Lutz E, Waalkes A, et al.
Bioconjug Chem . 2015 Jul; 26(8):1811-7. PMID: 26161996
Peptide ligands are used to increase the specificity of drug carriers to their target cells and to facilitate intracellular delivery. One method to identify such peptide ligands, phage display, enables...
10.
Kacherovsky N, Liu G, Jensen M, Pun S
Biotechnol Bioeng . 2015 Mar; 112(7):1429-36. PMID: 25808830
Engineered human T-cells are a promising therapeutic modality for cancer immunotherapy. T-cells expressing chimeric antigen receptors combined with additional genes to enhance T-cell proliferation, survival, or tumor targeting may further...