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Joshua Jenkins

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Articles 18
Citations 74
Followers 0
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Recent Articles
1.
Nan K, Wong K, Li D, Ying B, McRae J, Feig V, et al.
Nat Commun . 2024 Aug; 15(1):6749. PMID: 39117667
Ingestible electronics have the capacity to transform our ability to effectively diagnose and potentially treat a broad set of conditions. Current applications could be significantly enhanced by addressing poor electrode-tissue...
2.
Gilbert M, Fatima N, Jenkins J, OSullivan T, Schertel A, Halfon Y, et al.
Nature . 2024 Jul; 631(8022):913-919. PMID: 38987603
A defining pathological feature of most neurodegenerative diseases is the assembly of proteins into amyloid that form disease-specific structures. In Alzheimer's disease, this is characterized by the deposition of β-amyloid...
3.
Jimenez M, LHeureux J, Kolaya E, Liu G, Martin K, Ellis H, et al.
Nat Mater . 2024 Jul; 23(10):1436-1443. PMID: 38969782
Microorganisms typically used to produce food and pharmaceuticals are now being explored as medicines and agricultural supplements. However, maintaining high viability from manufacturing until use remains an important challenge, requiring...
4.
Eskew J, Reynolds Z, Jenkins J, Sridhar M
BMJ Case Rep . 2024 Feb; 17(2). PMID: 38423577
A woman in her 40s was involved in a motor vehicle collision and sustained a closed Hawkins type IV talar neck fracture dislocation. The injury was treated with reduction, percutaneous...
5.
Srinivasan S, Dosso J, Huang H, Selsing G, Alshareef A, Kuosmanen J, et al.
Sci Robot . 2024 Feb; 9(87):eadh8170. PMID: 38416855
Postoperative ileus (POI) is the leading cause of prolonged hospital stay after abdominal surgery and is characterized by a functional paralysis of the digestive tract, leading to symptoms such as...
6.
Liu G, Pickett M, Kuosmanen J, Ishida K, Madani W, White G, et al.
Nat Mater . 2024 Feb; 23(9):1292-1299. PMID: 38413810
Pills are a cornerstone of medicine but can be challenging to swallow. While liquid formulations are easier to ingest, they lack the capacity to localize therapeutics with excipients nor act...
7.
Srinivasan S, Alshareef A, Hwang A, Byrne C, Kuosmanen J, Ishida K, et al.
Sci Adv . 2023 Dec; 9(51):eadj3003. PMID: 38134286
Effective therapies for obesity require invasive surgical and endoscopic interventions or high patient adherence, making it challenging for patients with obesity to effectively manage their disease. Gastric mechanoreceptors sense distension...
8.
Bi J, Witt E, McGovern M, Cafi A, Rosenstock L, Pearson A, et al.
Adv Sci (Weinh) . 2023 Dec; 11(9):e2308346. PMID: 38084435
Modulation of autophagy, specifically its inhibition, stands to transform the capacity to effectively treat a broad range of cancers. However, the clinical efficacy of autophagy inhibitors has been inconsistent. To...
9.
Remlova E, Feig V, Kang Z, Patel A, Ballinger I, Ginzburg A, et al.
ACS Mater Lett . 2023 Sep; 5(9):2508-2517. PMID: 37680546
Delivering heat could enhance a wide range of biomedical therapeutic and diagnostic technologies, including long-term drug delivery devices and cancer treatments. To date, providing thermal energy is highly power-intensive, rendering...
10.
Srinivasan S, Alshareef A, Hwang A, Bryne C, Kuosmann J, Ishida K, et al.
bioRxiv . 2023 Jul; PMID: 37503258
Effective therapies for obesity either require invasive surgical or endoscopic interventions or high patient adherence, making it challenging for the nearly 42% of American adults who suffer from obesity to...