Gary H Cohen
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Explore the profile of Gary H Cohen including associated specialties, affiliations and a list of published articles.
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109
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5106
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Recent Articles
1.
Atanasiu D, Saw W, Friedman H, Cohen G
Viruses
. 2025 Feb;
17(2).
PMID: 40007004
Herpes simplex viruses (HSV-1 and HSV-2), which can be transmitted both orally and sexually, cause lifelong morbidity and in some cases, meningitis and encephalitis. While both the passive transfer of...
2.
Daniell H, Guo Y, Singh R, Karki U, Kulchar R, Wakade G, et al.
Mol Ther
. 2024 Dec;
33(1):184-200.
PMID: 39663701
Lack of Herpes Simplex Virus (HSV) vaccine, low vaccination rates of Influenza viruses, waning immunity and viral transmission after vaccination underscore the need to reduce viral loads at their transmission...
3.
Gonzalez-Del Pino G, Walsh Jr R, Atanasiu D, Cairns T, Saw W, Cohen G, et al.
bioRxiv
. 2024 Sep;
PMID: 39345478
infect nearly all humans for life, causing diseases that range from painful to life-threatening. These viruses penetrate cells by employing a complex apparatus composed of separate receptor-binding, signal-transmitting, and membrane-fusing...
4.
Boesze-Battaglia K, Cohen G, Bates P, Walker L, Zekavat A, Shenker B
Front Cell Infect Microbiol
. 2024 May;
14:1334224.
PMID: 38698905
cytolethal distending toxin (Cdt) is capable of intoxicating lymphocytes macrophages, mast cells and epithelial cells. Following Cdt binding to cholesterol, in the region of membrane lipid rafts, the CdtB and...
5.
de Lima L, Ferreira A, Awasthi S, Torres M, Friedman H, Cohen G, et al.
Cell Rep Phys Sci
. 2024 Jan;
4(9).
PMID: 38239491
Herpes simplex virus type 2 (HSV-2) infection, which is almost exclusively sexually transmitted, causes genital herpes. Although this lifelong and incurable infection is extremely widespread, currently there is no readily...
6.
Egan K, Awasthi S, Tebaldi G, Hook L, Naughton A, Fowler B, et al.
Viruses
. 2023 Jul;
15(7).
PMID: 37515169
HSV-1 disease is a significant public health burden causing orofacial, genital, cornea, and brain infection. We previously reported that a trivalent HSV-2 gC2, gD2, gE2 nucleoside-modified mRNA-lipid nanoparticle (LNP) vaccine...
7.
Awasthi S, Onishi M, Lubinski J, Fowler B, Naughton A, Hook L, et al.
Viruses
. 2023 May;
15(5).
PMID: 37243234
Herpes simplex virus type 2 (HSV-2) is a leading cause of genital ulcer disease and a major risk factor for acquisition and transmission of HIV. Frequent recurrent genital lesions and...
8.
Atanasiu D, Saw W, Cairns T, Friedman H, Eisenberg R, Cohen G
Viruses
. 2023 Apr;
15(4).
PMID: 37112875
Herpes simplex virus (HSV) requires four essential virion glycoproteins-gD, gH, gL, and gB-for virus entry and cell fusion. To initiate fusion, the receptor binding protein gD interacts with one of...
9.
Hook L, Awasthi S, Cairns T, Alameh M, Fowler B, Egan K, et al.
Viruses
. 2022 Mar;
14(3).
PMID: 35336946
The toxicity of mRNA-lipid nanoparticle (LNP) vaccines depends on the total mRNA-LNP dose. We established that the maximum tolerated dose of our trivalent mRNA-LNP genital herpes vaccine was 10 μg/immunization...
10.
Awasthi S, Knox J, Desmond A, Alameh M, Gaudette B, Lubinski J, et al.
J Clin Invest
. 2021 Oct;
131(23).
PMID: 34618692
Nucleoside-modified mRNA vaccines have gained global attention because of COVID-19. We evaluated a similar vaccine approach for preventing a chronic, latent genital infection rather than an acute respiratory infection. We...