Garrett A Soukup
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Explore the profile of Garrett A Soukup including associated specialties, affiliations and a list of published articles.
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27
Citations
1023
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Recent Articles
1.
Banks S, Pierce M, Soukup G
Mol Neurobiol
. 2019 Jul;
57(1):358-371.
PMID: 31359323
MicroRNAs (miRNAs, miRs) are short noncoding RNAs that act to repress expression of proteins from target mRNA transcripts. miRNAs influence many cellular processes including stemness, proliferation, differentiation, maintenance, and survival,...
2.
Weston M, Tarang S, Pierce M, Pyakurel U, Rocha-Sanchez S, McGee J, et al.
Sci Rep
. 2018 Feb;
8(1):3569.
PMID: 29476110
Germline mutations in Mir96, one of three co-expressed polycistronic miRNA genes (Mir96, Mir182, Mir183), cause hereditary hearing loss in humans and mice. Transgenic FVB/NCrl- Tg(GFAP-Mir183,Mir96,Mir182)MDW1 mice (Tg), which overexpress this...
3.
Ebeid M, Sripal P, Pecka J, Beisel K, Kwan K, Soukup G
PLoS One
. 2017 Jul;
12(7):e0180855.
PMID: 28686713
Over 5% of the global population suffers from disabling hearing loss caused by multiple factors including aging, noise exposure, genetic predisposition, or use of ototoxic drugs. Sensorineural hearing loss is...
4.
Zhang Q, Liu H, Soukup G, He D
PLoS One
. 2014 Nov;
9(11):e112857.
PMID: 25405349
Age-related hearing loss is a progressive sensorineural hearing loss that occurs during aging. Degeneration of the organ of Corti and atrophy of the lateral wall of the cochlear duct (or...
5.
Kim J, Jeong S, Kertsburg A, Soukup G, Lee S
ACS Chem Biol
. 2014 Sep;
9(11):2491-5.
PMID: 25265474
Gene therapeutic approaches are needed that can simultaneously induce the well-controlled expression of therapeutic genes and suppress the expression of disease-causing genes for maximization of their efficacy. To address this...
6.
Liu H, Pecka J, Zhang Q, Soukup G, Beisel K, He D
J Neurosci
. 2014 Aug;
34(33):11085-95.
PMID: 25122905
Inner hair cells (IHCs) and outer hair cells (OHCs) are the two types of sensory receptor cells that are critical for hearing in the mammalian cochlea. IHCs and OHCs have...
7.
8.
Barritt L, Miller J, Scheetz L, Gardner K, Pierce M, Soukup G, et al.
Indian J Hum Genet
. 2013 May;
18(3):310-9.
PMID: 23716939
Background: Orofacial clefts are common worldwide and result from insufficient growth and/or fusion during the genesis of the derivatives of the first pharyngeal arch and the frontonasal prominence. Recent studies...
9.
Identifying microRNAs involved in degeneration of the organ of corti during age-related hearing loss
Zhang Q, Liu H, McGee J, Walsh E, Soukup G, He D
PLoS One
. 2013 May;
8(4):e62786.
PMID: 23646144
MicroRNAs (miRNAs), a class of short non-coding RNAs that regulate the expression of mRNA targets, are important regulators of cellular senescence and aging. We questioned which miRNAs are involved in...
10.
Weston M, Pierce M, Jensen-Smith H, Fritzsch B, Rocha-Sanchez S, Beisel K, et al.
Dev Dyn
. 2011 Mar;
240(4):808-19.
PMID: 21360794
MicroRNAs (miRNAs) post-transcriptionally repress complementary target gene expression and can contribute to cell differentiation. The coordinate expression of miRNA-183 family members (miR-183, miR-96, and miR-182) has been demonstrated in sensory...