Gareth Peat
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Explore the profile of Gareth Peat including associated specialties, affiliations and a list of published articles.
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6
Citations
988
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Recent Articles
1.
Mountjoy E, Schmidt E, Carmona M, Schwartzentruber J, Peat G, Miranda A, et al.
Nat Genet
. 2021 Oct;
53(11):1527-1533.
PMID: 34711957
Genome-wide association studies (GWASs) have identified many variants associated with complex traits, but identifying the causal gene(s) is a major challenge. In the present study, we present an open resource...
2.
Ochoa D, Hercules A, Carmona M, Suveges D, Gonzalez-Uriarte A, Malangone C, et al.
Nucleic Acids Res
. 2020 Nov;
49(D1):D1302-D1310.
PMID: 33196847
The Open Targets Platform (https://www.targetvalidation.org/) provides users with a queryable knowledgebase and user interface to aid systematic target identification and prioritisation for drug discovery based upon underlying evidence. It is...
3.
Ghoussaini M, Mountjoy E, Carmona M, Peat G, Schmidt E, Hercules A, et al.
Nucleic Acids Res
. 2020 Oct;
49(D1):D1311-D1320.
PMID: 33045747
Open Targets Genetics (https://genetics.opentargets.org) is an open-access integrative resource that aggregates human GWAS and functional genomics data including gene expression, protein abundance, chromatin interaction and conformation data from a wide...
4.
Peat G, Jones W, Nuhn M, Marugan J, Newell W, Dunham I, et al.
Bioinformatics
. 2020 Jan;
36(9):2936-2937.
PMID: 31930349
Motivation: Genome-wide association studies (GWAS) are a powerful method to detect even weak associations between variants and phenotypes; however, many of the identified associated variants are in non-coding regions, and...
5.
Carvalho-Silva D, Pierleoni A, Pignatelli M, Ong C, Fumis L, Karamanis N, et al.
Nucleic Acids Res
. 2018 Nov;
47(D1):D1056-D1065.
PMID: 30462303
The Open Targets Platform integrates evidence from genetics, genomics, transcriptomics, drugs, animal models and scientific literature to score and rank target-disease associations for drug target identification. The associations are displayed...
6.
Garcia-Alonso L, Iorio F, Matchan A, Fonseca N, Jaaks P, Peat G, et al.
Cancer Res
. 2017 Dec;
78(3):769-780.
PMID: 29229604
Transcriptional dysregulation induced by aberrant transcription factors (TF) is a key feature of cancer, but its global influence on drug sensitivity has not been examined. Here, we infer the transcriptional...