Gautier Koscielny
Overview
Explore the profile of Gautier Koscielny including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
2193
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0
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Recent Articles
1.
Ochoa D, Hercules A, Carmona M, Suveges D, Gonzalez-Uriarte A, Malangone C, et al.
Nucleic Acids Res
. 2020 Nov;
49(D1):D1302-D1310.
PMID: 33196847
The Open Targets Platform (https://www.targetvalidation.org/) provides users with a queryable knowledgebase and user interface to aid systematic target identification and prioritisation for drug discovery based upon underlying evidence. It is...
2.
Ghoussaini M, Mountjoy E, Carmona M, Peat G, Schmidt E, Hercules A, et al.
Nucleic Acids Res
. 2020 Oct;
49(D1):D1311-D1320.
PMID: 33045747
Open Targets Genetics (https://genetics.opentargets.org) is an open-access integrative resource that aggregates human GWAS and functional genomics data including gene expression, protein abundance, chromatin interaction and conformation data from a wide...
3.
Carvalho-Silva D, Pierleoni A, Pignatelli M, Ong C, Fumis L, Karamanis N, et al.
Nucleic Acids Res
. 2018 Nov;
47(D1):D1056-D1065.
PMID: 30462303
The Open Targets Platform integrates evidence from genetics, genomics, transcriptomics, drugs, animal models and scientific literature to score and rank target-disease associations for drug target identification. The associations are displayed...
4.
Khaladkar M, Koscielny G, Hasan S, Agarwal P, Dunham I, Rajpal D, et al.
Drug Discov Today
. 2017 Sep;
22(12):1800-1807.
PMID: 28919242
The recently developed Open Targets platform consolidates a wide range of comprehensive evidence associating known and potential drug targets with human diseases. We have harnessed the integrated data from this...
5.
Koscielny G, An P, Carvalho-Silva D, Cham J, Fumis L, Gasparyan R, et al.
Nucleic Acids Res
. 2016 Dec;
45(D1):D985-D994.
PMID: 27899665
We have designed and developed a data integration and visualization platform that provides evidence about the association of known and potential drug targets with diseases. The platform is designed to...
6.
Sarntivijai S, Vasant D, Jupp S, Saunders G, Bento A, Gonzalez D, et al.
J Biomed Semantics
. 2016 Mar;
7:8.
PMID: 27011785
Background: The Centre for Therapeutic Target Validation (CTTV - https://www.targetvalidation.org/) was established to generate therapeutic target evidence from genome-scale experiments and analyses. CTTV aims to support the validity of therapeutic...
7.
Koscielny G, Yaikhom G, Iyer V, Meehan T, Morgan H, Atienza-Herrero J, et al.
Nucleic Acids Res
. 2013 Nov;
42(Database issue):D802-9.
PMID: 24194600
The International Mouse Phenotyping Consortium (IMPC) web portal (http://www.mousephenotype.org) provides the biomedical community with a unified point of access to mutant mice and rich collection of related emerging and existing...
8.
Spivakov M, Akhtar J, Kheradpour P, Beal K, Girardot C, Koscielny G, et al.
Genome Biol
. 2012 Sep;
13(9):R49.
PMID: 22950968
Background: Advances in sequencing technology have boosted population genomics and made it possible to map the positions of transcription factor binding sites (TFBSs) with high precision. Here we investigate TFBS...
9.
Megy K, Emrich S, Lawson D, Campbell D, Dialynas E, Hughes D, et al.
Nucleic Acids Res
. 2011 Dec;
40(Database issue):D729-34.
PMID: 22135296
VectorBase (http://www.vectorbase.org) is a NIAID-supported bioinformatics resource for invertebrate vectors of human pathogens. It hosts data for nine genomes: mosquitoes (three Anopheles gambiae genomes, Aedes aegypti and Culex quinquefasciatus), tick...
10.
Flicek P, Amode M, Barrell D, Beal K, Brent S, Carvalho-Silva D, et al.
Nucleic Acids Res
. 2011 Nov;
40(Database issue):D84-90.
PMID: 22086963
The Ensembl project (http://www.ensembl.org) provides genome resources for chordate genomes with a particular focus on human genome data as well as data for key model organisms such as mouse, rat...