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Gangwen Han

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Articles 38
Citations 1891
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Recent Articles
1.
Gao N, Wang J, Zhao Z, Chu X, Lv B, Han G, et al.
Sci Rep . 2025 Jan; 15(1):1119. PMID: 39774300
Accurate acne severity grading is crucial for effective clinical treatment and timely follow-up management. Although some artificial intelligence methods have been developed to automate the process of acne severity grading,...
2.
Ma X, Wen G, Zhao Z, Lu L, Li T, Gao N, et al.
Sci Rep . 2024 Apr; 14(1):8429. PMID: 38600101
Vulvar lichen sclerosus (VLS) is a chronic and progressive dermatologic condition that can cause physical dysfunction, disfigurement, and impaired quality of life. However, the etiology of VLS remains unknown. The...
3.
Ma X, Li T, Han G
Clin Cosmet Investig Dermatol . 2023 Dec; 16:3521-3525. PMID: 38089016
Atopic dermatitis and psoriasis are both common chronic inflammatory skin conditions that can significantly affect the quality of life for individuals affected by them. With the growing use of biologic...
4.
Gao N, Lu L, Ma X, Liu Z, Yang S, Han G
Exp Dermatol . 2021 Oct; 31(3):320-329. PMID: 34623712
Abnormal activation of fibroblasts plays a crucial role in keloid development. However, the mechanism of fibroblast activation remains to be determined. YAP/TAZ are key molecules in the Hippo signalling pathway...
5.
Li H, Zhang C, Bian L, Deng H, Blevins M, Han G, et al.
J Invest Dermatol . 2021 Jul; 142(2):390-401. PMID: 34293351
Psoriasis is a chronic immune-mediated disease characterized by excessive proliferation of epidermal keratinocytes and increased immune cell infiltration to the skin. Although it is well-known that psoriasis pathogenesis is driven...
6.
Ma X, Lu L, Zhao Z, Cai M, Gao N, Han G
Lipids Health Dis . 2020 Jul; 19(1):171. PMID: 32677954
Background: Senile pruritus is common, yet its etiology remains unknown. Aging-associated skin barrier defects and skin surface lipid (SSL) alterations have been postulated to play important roles in its occurrence....
7.
Tian S, Han G, Lu L, Meng X
World J Surg Oncol . 2020 Mar; 18(1):56. PMID: 32183822
Background: Numerous literatures have demonstrated that circular RNAs (circRNAs) are involved in multiple types of tumors. However, the effects of circRNAs in melanoma are not very clear. In this study,...
8.
Hernandez A, Young C, Bian L, Weigel K, Nolan K, Frederick B, et al.
Clin Cancer Res . 2020 Mar; 26(12):3058-3070. PMID: 32139402
Purpose: loss causes genomic instability and the initiation/progression of head and neck squamous cell carcinoma (HNSCC). Here, we study whether loss sensitizes HNSCCs to olaparib (PARP inhibitor) in combination with...
9.
Li F, Bian L, Iriyama S, Jian Z, Fan B, Luo J, et al.
J Invest Dermatol . 2018 Nov; 139(4):940-950. PMID: 30423327
We assessed the roles of Smad7 in skin inflammation and wound healing using genetic and pharmacological approaches. In K5.TGFβ1/K5.Smad7 bigenic (double transgenic) mice, Smad7 transgene expression reversed transforming growth factor...
10.
Fan B, Wang T, Bian L, Jian Z, Wang D, Li F, et al.
Int J Biol Sci . 2018 Aug; 14(10):1163-1174. PMID: 30123066
The endogenous small GTPase, Rac1, plays a critical role during normal skin wound healing. It remains to be determined whether endogenous Rac1 can be appropriately activated in chronic wounds; if...