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Gamze Ates

Explore the profile of Gamze Ates including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 420
Followers 0
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Recent Articles
1.
Lara O, Janssen P, Mambretti M, De Pauw L, Ates G, Mackens L, et al.
Brain Behav Immun . 2024 Mar; 118:275-286. PMID: 38447884
xCT (Slc7a11), the specific subunit of the cystine/glutamate antiporter system x, is present in the brain and on immune cells, where it is known to modulate behavior and inflammatory responses....
2.
Fan R, Satilmis H, Vandewalle N, Verheye E, de Bruyne E, Menu E, et al.
Blood Cancer J . 2023 Dec; 13(1):188. PMID: 38110349
Acute Myeloid Leukemia (AML) is a heterogeneous disease with limited treatment options and a high demand for novel targeted therapies. Since myeloid-related protein S100A9 is abundantly expressed in AML, we...
3.
Ates G, Taguchi T, Maher P
Mol Neurobiol . 2023 Oct; 61(4):2165-2175. PMID: 37864765
There are currently no drugs that meaningfully slow down the progression of Huntington's disease (HD). Moreover, drug candidates against a single molecular target have not had significant success. Therefore, a...
4.
Belo Do Nascimento I, Ates G, Desmet N, Beckers P, Massie A, Hermans E
Biomolecules . 2023 Aug; 13(8). PMID: 37627248
Alterations in the activity of the regulator of cell metabolism AMP-activated protein kinase (AMPK) have been reported in motor neurons from patients and animal models of amyotrophic lateral sclerosis (ALS)....
5.
Pan Z, Van den Bossche J, Rodriguez-Aznar E, Janssen P, Lara O, Ates G, et al.
Cell Death Dis . 2023 Aug; 14(8):536. PMID: 37604805
Acinar cell dedifferentiation is one of the most notable features of acute and chronic pancreatitis. It can also be the initial step that facilitates pancreatic cancer development. In the present...
6.
Akin N, Ates G, von Mengden L, Herta A, Meriggioli C, Billooye K, et al.
Biol Reprod . 2023 Aug; 109(4):432-449. PMID: 37531262
In vitro maturation (IVM) is an alternative assisted reproductive technology with reduced hormone-related side effects and treatment burden compared to conventional IVF. Capacitation (CAPA)-IVM is a bi-phasic IVM system with...
7.
Rodrigues R, Stinckens M, Ates G, Vanhaecke T
Methods Mol Biol . 2023 May; 2644:237-245. PMID: 37142926
The neutral red uptake (NRU) assay is a cell viability assay that can be used for the assessment of compound-induced cytotoxicity. It is based on the ability of living cells...
8.
Van der Vreken A, Oudaert I, Ates G, Faict S, Vlummens P, Satilmis H, et al.
J Pathol . 2023 Feb; 260(2):112-123. PMID: 36807305
Multiple myeloma (MM) remains an incurable haematological malignancy despite substantial advances in therapy. Hypoxic bone marrow induces metabolic rewiring in MM cells contributing to survival and drug resistance. Therefore, targeting...
9.
Satilmis H, Verheye E, Vlummens P, Oudaert I, Vandewalle N, Fan R, et al.
J Pathol . 2022 Oct; 259(1):69-80. PMID: 36245401
While multi-drug combinations and continuous treatment have become standard for multiple myeloma, the disease remains incurable. Repurposing drugs that are currently used for other indications could provide a novel approach...
10.
Belo Do Nascimento I, Verfaillie M, Ates G, Beckers P, Joris V, Desmet N, et al.
Cells . 2022 Jun; 11(11). PMID: 35681495
Energy homeostasis in the central nervous system largely depends on astrocytes, which provide metabolic support and protection to neurons. Astrocytes also ensure the clearance of extracellular glutamate through high-affinity transporters,...