Gaia Fumagalli
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Explore the profile of Gaia Fumagalli including associated specialties, affiliations and a list of published articles.
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12
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204
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Recent Articles
1.
Garcia C, Bernardes C, Piedade M, Fumagalli G, Colombo E, Diaz-Lanza A, et al.
ACS Omega
. 2022 Dec;
7(48):44180-44186.
PMID: 36506152
6,7-Dehydroroyleanone (DHR) is a caspase-induced cytotoxic abietane diterpene, frequently found on spp. A pharmaceutical formulation consisting of a DHR-squalene conjugate was synthesized and analyzed by different techniques such as scanning...
2.
Fumagalli G, Mazza D, Christodoulou M, Damia G, Ricci F, Perdicchia D, et al.
Chempluschem
. 2020 Jan;
80(9):1380-1383.
PMID: 31973361
Cyclopamine- and paclitaxel-containing hetero-nanoparticles generated by self-assembly show combined efficacy in the treatment of three different cancer cell lines. The use of ternary combination with the addition of a dye-squalene...
3.
Fumagalli G, Polito L, Colombo E, Foschi F, Christodoulou M, Galeotti F, et al.
ACS Med Chem Lett
. 2019 Apr;
10(4):611-614.
PMID: 30996805
The design and the synthesis of new self-assembling conjugates is reported. The target compounds are characterized by the presence of a self-immolative linker that secures a controlled release induced by...
4.
Fumagalli G, Giorgi G, Vagvolgyi M, Colombo E, Christodoulou M, Collico V, et al.
ACS Med Chem Lett
. 2018 May;
9(5):468-471.
PMID: 29795761
Heteronanoparticles (H-NPs) consisting of conjugates characterized by a squalene tail linked to doxorubicin and ecdysteroid derivatives are presented. Biological evaluation on A2780ADR cell line confirms not only the maintenance of...
5.
Fumagalli G, Stella B, Pastushenko I, Ricci F, Christodoulou M, Damia G, et al.
ACS Med Chem Lett
. 2017 Sep;
8(9):953-957.
PMID: 28947943
The preparation of heteronanoparticles (NPs) with doxorubicin (DOXO) and cyclopamine (CYP) conjugates is presented. Biological evaluation on A431 cell lines confirms the maintenance of the activity of the parental drugs....
6.
Bonandi E, Christodoulou M, Fumagalli G, Perdicchia D, Rastelli G, Passarella D
Drug Discov Today
. 2017 Jul;
22(10):1572-1581.
PMID: 28676407
1,2,3-Triazole is a well-known scaffold that has a widespread occurrence in different compounds characterized by several bioactivities, such as antimicrobial, antiviral, and antitumor effects. Moreover, the structural features of 1,2,3-triazole...
7.
Fumagalli G, Christodoulou M, Riva B, Revuelta I, Marucci C, Collico V, et al.
Org Biomol Chem
. 2017 Feb;
15(7):1725.
PMID: 28150007
Correction for 'Self-assembled 4-(1,2-diphenylbut-1-en-1-yl)aniline based nanoparticles: podophyllotoxin and aloin as building blocks' by Gaia Fumagalli, et al., Org. Biomol. Chem., 2017, DOI: 10.1039/c6ob02591a.
8.
Fumagalli G, Christodoulou M, Riva B, Revuelta I, Marucci C, Collico V, et al.
Org Biomol Chem
. 2017 Jan;
15(5):1106-1109.
PMID: 28093593
The ability of 4-(1,2-diphenylbut-1-en-1-yl)aniline as a self-assembly inducer is reported. The conjugation of this moiety with aloin or podophyllotoxin resulted in spherical nanoparticles that were characterized by Dynamic Light Scattering...
9.
Fumagalli G, Marucci C, Christodoulou M, Stella B, Dosio F, Passarella D
Drug Discov Today
. 2016 Jun;
21(8):1321-9.
PMID: 27329268
Self-assembly drug conjugate preparation is a promising approach to improve activity and penetration through physiological barriers of potent small molecules, as well as to reduce any side effects. Drug conjugates...
10.
Perdicchia D, Christodoulou M, Fumagalli G, Calogero F, Marucci C, Passarella D
Int J Mol Sci
. 2015 Dec;
17(1).
PMID: 26712740
2-Piperidineethanol (1) and its corresponding N-protected aldehyde (2) were used for the synthesis of several natural and synthetic compounds. The existence of a stereocenter at position 2 of the piperidine...