Gaetano Di Chiara
Overview
Explore the profile of Gaetano Di Chiara including associated specialties, affiliations and a list of published articles.
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Articles
53
Citations
2011
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Recent Articles
1.
Heinz A, Gutwinski S, Bahr N, Spanagel R, Di Chiara G
Addict Biol
. 2024 Apr;
29(4):e13379.
PMID: 38588458
One of the leading drug addiction theories states that habits and the underlying neural process of a ventral to dorsal striatal shift are the building blocks of compulsive drug-seeking behaviour...
2.
Tocco G, Laus A, Vanejevs M, Ture A, Mostallino R, Pintori N, et al.
Arch Pharm (Weinheim)
. 2022 Nov;
356(1):e2200432.
PMID: 36328777
The development of novel μ-opioid receptor (MOR) antagonists is one of the main objectives of drug discovery and development. Based on a simplified version of the morphinan scaffold, 3-[3-(phenalkylamino)cyclohexyl]phenol analogs...
3.
De Luca M, Tocco G, Mostallino R, Laus A, Caria F, Musa A, et al.
Neuropharmacology
. 2022 Sep;
221:109263.
PMID: 36154843
Recent trends of opioid abuse and related fatalities have highlighted the critical role of Novel Synthetic Opioids (NSOs). We studied the μ-opioid-like properties of isotonitazene (ITZ), metonitazene (MTZ), and piperidylthiambutene...
4.
Pintori N, Castelli M, Miliano C, Simola N, Fadda P, Fattore L, et al.
Br J Pharmacol
. 2021 Apr;
178(17):3476-3497.
PMID: 33837969
Background And Purpose: Spice/K2 herbal mixtures, containing synthetic cannabinoids such as JWH-018, have been marketed as marijuana surrogates since 2004. JWH-018 has cannabinoid CB receptor-dependent reinforcing properties and acutely increases...
5.
Lecca D, Scifo A, Pisanu A, Valentini V, Piras G, Sil A, et al.
Neuropharmacology
. 2020 Feb;
166:107974.
PMID: 32007624
On the basis of epidemiological studies it has been proposed that cannabis use plays a causal role in the abuse of highly addictive drugs (Gateway Hypothesis). However, epidemiological studies are...
6.
Heinz A, Daedelow L, Wackerhagen C, Di Chiara G
Addict Biol
. 2019 Mar;
25(2):e12735.
PMID: 30896084
With the development of the ICD-11, the debate about classifying certain psychoactive substances such as antidepressant medication and caffeine as drugs of dependence is ignited again. We argue that any...
7.
De Luca M, Buczynski M, Di Chiara G
Addict Biol
. 2018 Jun;
23(6):1207-1222.
PMID: 29949237
Loren (Larry) H. Parsons passed away at the age of 51. In spite of his premature departure, Larry much contributed to the drug abuse field. Since his graduate studies for...
8.
Cadoni C, Pisanu A, Simola N, Frau L, Porceddu P, Corongiu S, et al.
Neuropharmacology
. 2017 Jun;
123:385-394.
PMID: 28603026
Although MDMA (3,4-methylendioxymethamphetamine, ecstasy) neurotoxicity in serotonin neurons is largely recognized in a wide variety of species including man, neurotoxicity in dopamine (DA) neurons is thought to be species-specific. MDMA...
9.
Bassareo V, Cucca F, Frau R, Di Chiara G
Front Behav Neurosci
. 2017 May;
11:71.
PMID: 28507512
Ethanol, like other substances of abuse, preferentially increases dopamine (DA) transmission in the rat nucleus accumbens (NAc) following passive administration. It remains unclear, however, whether ethanol also increases NAc DA...
10.
Orsolini L, Papanti D, Corkery J, De Luca M, Cadoni C, Di Chiara G, et al.
CNS Neurol Disord Drug Targets
. 2017 Apr;
16(5):585-591.
PMID: 28412917
Background: Substance use, including cannabis, has been documented amongst women both in the pre-conception period and during pregnancy, particularly during the 1st trimester, which is clearly the most critical period...