Does Compulsion Explain Addiction?

Overview

Journal Addict Biol

Specialty Psychiatry

Date 2024 Apr 8

PMID 38588458

Authors

Andreas Heinz

Stefan Gutwinski

Nadja Samia Bahr

Rainer Spanagel

Gaetano Di Chiara

Affiliations

Soon will be listed here.

Abstract

One of the leading drug addiction theories states that habits and the underlying neural process of a ventral to dorsal striatal shift are the building blocks of compulsive drug-seeking behaviour and that compulsion is the maladaptive persistence of responding despite adverse consequences. Here we discuss that compulsive behaviour as defined primarily from the perspective of animal experimentation falls short of the clinical phenomena and their neurobiological correlates. Thus for the human condition, the concept of compulsive habbits should be critically addressed and potentially revised.

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