Gad Abraham
Overview
Explore the profile of Gad Abraham including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
2113
Followers
0
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Recent Articles
1.
Ritchie S, Taylor H, Liang Y, Manikpurage H, Pennells L, Foguet C, et al.
medRxiv
. 2024 Sep;
PMID: 39228710
Combining information from multiple GWASs for a disease and its risk factors has proven a powerful approach for development of polygenic risk scores (PRSs). This may be particularly useful for...
2.
Bakker M, Kanning J, Abraham G, Martinsen A, Winsvold B, Zwart J, et al.
Stroke
. 2023 Jan;
54(3):810-818.
PMID: 36655558
Background: Recently, common genetic risk factors for intracranial aneurysm (IA) and aneurysmal subarachnoid hemorrhage (ASAH) were found to explain a large amount of disease heritability and therefore have potential to...
3.
Neumann J, Riaz M, Bakshi A, Polekhina G, Thao L, Nelson M, et al.
Circ Genom Precis Med
. 2021 Dec;
15(1):e003429.
PMID: 34949098
Background: The use of a polygenic risk score (PRS) to improve risk prediction of coronary heart disease (CHD) events has been demonstrated to have clinical utility in the general adult...
4.
Ritchie S, Lambert S, Arnold M, Teo S, Lim S, Scepanovic P, et al.
Nat Metab
. 2021 Nov;
3(11):1476-1483.
PMID: 34750571
Cardiometabolic diseases are frequently polygenic in architecture, comprising a large number of risk alleles with small effects spread across the genome. Polygenic scores (PGS) aggregate these into a metric representing...
5.
Abraham G, Rutten-Jacobs L, Inouye M
Stroke
. 2021 Aug;
52(9):2983-2991.
PMID: 34399584
Early prediction of risk of cardiovascular disease (CVD), including stroke, is a cornerstone of disease prevention. Clinical risk scores have been widely used for predicting CVD risk from known risk...
6.
Neumann J, Riaz M, Bakshi A, Polekhina G, Thao L, Nelson M, et al.
Stroke
. 2021 May;
52(9):2882-2891.
PMID: 34039031
Background And Purpose: Polygenic risk scores (PRSs) can be used to predict ischemic stroke (IS). However, further validation of PRS performance is required in independent populations, particularly older adults in...
7.
Lambert S, Gil L, Jupp S, Ritchie S, Xu Y, Buniello A, et al.
Nat Genet
. 2021 Mar;
53(4):420-425.
PMID: 33692568
No abstract available.
8.
Sun L, Pennells L, Kaptoge S, Nelson C, Ritchie S, Abraham G, et al.
PLoS Med
. 2021 Jan;
18(1):e1003498.
PMID: 33444330
Background: Polygenic risk scores (PRSs) can stratify populations into cardiovascular disease (CVD) risk groups. We aimed to quantify the potential advantage of adding information on PRSs to conventional risk factors...
9.
Canovas R, Cobb J, Brozynska M, Bowes J, Li Y, Smith S, et al.
Ann Rheum Dis
. 2020 Sep;
79(12):1572-1579.
PMID: 32887683
Objectives: Juvenile idiopathic arthritis (JIA) is an autoimmune disease and a common cause of chronic disability in children. Diagnosis of JIA is based purely on clinical symptoms, which can be...
10.
Abraham G, Malik R, Yonova-Doing E, Salim A, Wang T, Danesh J, et al.
Nat Commun
. 2020 Feb;
11(1):1036.
PMID: 32080192
An amendment to this paper has been published and can be accessed via a link at the top of the paper.