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Gabrielle Haas

Explore the profile of Gabrielle Haas including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 390
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Recent Articles
1.
Silva E, de Faria I, Ferreira A, Jiran T, Estevez-Castro C, Armache J, et al.
PLoS Pathog . 2025 Feb; 21(2):e1012184. PMID: 39899642
RNA interference (RNAi) mediated by the small interfering RNA (siRNA) pathway is a major antiviral mechanism in insects. This pathway is triggered when double-stranded RNA (dsRNA) produced during virus replication...
2.
Hedelin L, Thiebaut A, Huang J, Li X, Lemoine A, Haas G, et al.
Mol Biol Evol . 2024 Feb; 41(3). PMID: 38377349
Viruses represent a major threat to all animals, which defend themselves through induction of a large set of virus-stimulated genes that collectively control the infection. In vertebrates, these genes include...
3.
Cai H, Li L, Slavik K, Huang J, Yin T, Ai X, et al.
Immunity . 2023 Sep; 56(9):1991-2005.e9. PMID: 37659413
In mammals, the enzyme cGAS senses the presence of cytosolic DNA and synthesizes the cyclic dinucleotide (CDN) 2'3'-cGAMP, which triggers STING-dependent immunity. In Drosophila melanogaster, two cGAS-like receptors (cGLRs) produce...
4.
Geldreich A, Haas G, Kubina J, Bouton C, Tanguy M, Erhardt M, et al.
PLoS One . 2017 Dec; 12(12):e0189062. PMID: 29253877
Cauliflower mosaic virus (CaMV) TAV protein (TransActivator/Viroplasmin) plays a pivotal role during the infection cycle since it activates translation reinitiation of viral polycistronic RNAs and suppresses RNA silencing. It is...
5.
Alsaleh G, Nehmar R, Bluml S, Schleiss C, Ostermann E, Dillenseger J, et al.
Arthritis Rheumatol . 2016 Feb; 68(8):1839-48. PMID: 26882526
Objective: While the regulatory role of individual microRNAs (miRNAs) in rheumatoid arthritis (RA) is well established, the role of DICER1 in the pathogenesis of the disease has not yet been...
6.
Haas G, Cetin S, Messmer M, Chane-Woon-Ming B, Terenzi O, Chicher J, et al.
Nucleic Acids Res . 2016 Jan; 44(6):2873-87. PMID: 26809675
The mechanism by which micro (mi)RNAs control their target gene expression is now well understood. It is however less clear how the level of miRNAs themselves is regulated. Under specific...
7.
Haas G, Azevedo J, Moissiard G, Geldreich A, Himber C, Bureau M, et al.
EMBO J . 2015 Aug; 34(20):2591-2. PMID: 26290338
No abstract available.
8.
Braun J, Truffault V, Boland A, Huntzinger E, Chang C, Haas G, et al.
Nat Struct Mol Biol . 2012 Nov; 19(12):1324-31. PMID: 23142987
The removal of the mRNA 5' cap structure by the decapping enzyme DCP2 leads to rapid 5'→3' mRNA degradation by XRN1, suggesting that the two processes are coordinated, but the...
9.
Braun J, Tritschler F, Haas G, Igreja C, Truffault V, Weichenrieder O, et al.
EMBO J . 2010 Jun; 29(14):2368-80. PMID: 20543818
Pat proteins regulate the transition of mRNAs from a state that is translationally active to one that is repressed, committing targeted mRNAs to degradation. Pat proteins contain a conserved N-terminal...
10.
Haas G, Braun J, Igreja C, Tritschler F, Nishihara T, Izaurralde E
J Cell Biol . 2010 Apr; 189(2):289-302. PMID: 20404111
Decapping of eukaryotic messenger RNAs (mRNAs) occurs after they have undergone deadenylation, but how these processes are coordinated is poorly understood. In this study, we report that Drosophila melanogaster HPat...