Felix Tritschler
Overview
Explore the profile of Felix Tritschler including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
15
Citations
629
Followers
0
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Recent Articles
1.
Tritschler F, Binder M, Handel F, Burghardt D, Dietrich P, Liedl R
Ground Water
. 2019 May;
58(1):125-131.
PMID: 31037740
Locally collected precipitation water can be actively used as a groundwater tracer solution based on four inherent tracer signals: electrical conductivity, stable isotopic signatures of deuterium [δ H], oxygen-18 [δ...
2.
Lin C, Tritschler F, Lee K, Gu M, Rice C, Ha T
Protein Sci
. 2017 Feb;
26(7):1391-1403.
PMID: 28176403
Non-structural protein 3 (NS3) is an essential enzyme and a therapeutic target of hepatitis C virus (HCV). Compared to NS3-catalyzed nucleic acids unwinding, its translation on single stranded nucleic acids...
3.
Braun J, Tritschler F, Haas G, Igreja C, Truffault V, Weichenrieder O, et al.
EMBO J
. 2010 Jun;
29(14):2368-80.
PMID: 20543818
Pat proteins regulate the transition of mRNAs from a state that is translationally active to one that is repressed, committing targeted mRNAs to degradation. Pat proteins contain a conserved N-terminal...
4.
Boland A, Tritschler F, Heimstadt S, Izaurralde E, Weichenrieder O
EMBO Rep
. 2010 Jun;
11(7):522-7.
PMID: 20539312
Argonaute (AGO) proteins are core components of RNA-induced silencing complexes and have essential roles in RNA-mediated gene silencing. They are characterized by a bilobal architecture, consisting of one lobe containing...
5.
Haas G, Braun J, Igreja C, Tritschler F, Nishihara T, Izaurralde E
J Cell Biol
. 2010 Apr;
189(2):289-302.
PMID: 20404111
Decapping of eukaryotic messenger RNAs (mRNAs) occurs after they have undergone deadenylation, but how these processes are coordinated is poorly understood. In this study, we report that Drosophila melanogaster HPat...
6.
Tritschler F, Huntzinger E, Izaurralde E
Nat Rev Mol Cell Biol
. 2010 Apr;
11(5):379-84.
PMID: 20379206
GW182 proteins have emerged as key components of microRNA (miRNA) silencing complexes in animals. Although the precise molecular function of GW182 proteins is not fully understood, new findings indicate that...
7.
Tritschler F, Braun J, Motz C, Igreja C, Haas G, Truffault V, et al.
Proc Natl Acad Sci U S A
. 2009 Dec;
106(51):21591-6.
PMID: 19966221
DCP1 stimulates the decapping enzyme DCP2, which removes the mRNA 5' cap structure committing mRNAs to degradation. In multicellular eukaryotes, DCP1-DCP2 interaction is stabilized by additional proteins, including EDC4. However,...
8.
Eulalio A, Tritschler F, Izaurralde E
RNA
. 2009 Jun;
15(8):1433-42.
PMID: 19535464
GW182 family proteins interact directly with Argonaute proteins and are required for miRNA-mediated gene silencing in animal cells. The domains of the GW182 proteins have recently been studied to determine...
9.
Ronellenfitsch M, Brucker D, Burger M, Wolking S, Tritschler F, Rieger J, et al.
Brain
. 2009 May;
132(Pt 6):1509-22.
PMID: 19416948
Although inhibition of the epidermal growth factor receptor is a plausible therapy for malignant gliomas that, in vitro, enhances apoptosis, the results of clinical trials have been disappointing. The mammalian...
10.
Eulalio A, Tritschler F, Buttner R, Weichenrieder O, Izaurralde E, Truffault V
Nucleic Acids Res
. 2009 Mar;
37(9):2974-83.
PMID: 19295135
Proteins of the GW182 family interact with Argonaute proteins and are required for miRNA-mediated gene silencing. These proteins contain two structural domains, an ubiquitin-associated (UBA) domain and an RNA recognition...