G W Teebor
Overview
Explore the profile of G W Teebor including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
46
Citations
652
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Boorstein R, Cummings Jr A, Marenstein D, Chan M, Ma Y, Neubert T, et al.
J Biol Chem
. 2001 Aug;
276(45):41991-7.
PMID: 11526119
Purification from calf thymus of a DNA N-glycosylase activity (HMUDG) that released 5-hydroxymethyluracil (5hmUra) from the DNA of Bacillus subtilis phage SPO1 was undertaken. Analysis of the most purified fraction...
2.
Marenstein D, Ocampo M, Chan M, Altamirano A, Basu A, Boorstein R, et al.
J Biol Chem
. 2001 Apr;
276(24):21242-9.
PMID: 11287425
Human endonuclease III (hNth1) is a DNA glycosylase/apurinic/apyrimidinic (AP) lyase that initiates base excision repair of pyrimidines modified by reactive oxygen species, ionizing, and ultraviolet radiation. Using duplex 2'-deoxyribose oligonucleotides...
3.
Mi L, Chaung W, Horowitz R, Teebor G, Boorstein R
Carcinogenesis
. 2001 Feb;
22(1):179-86.
PMID: 11159757
We have demonstrated previously that the toxicity of 5-hydroxymethyl-2'-deoxyuridine (hmdUrd) to Chinese hamster fibroblasts (V79 cells) results from enzymatic removal of large numbers of hydroxymethyluracil residues from the DNA backbone...
4.
Chheda A, Teebor G, Cunningham R
Methods
. 2000 Oct;
22(2):180-7.
PMID: 11020333
This paper describes a reductive amination crosslinking protocol that facilitates identification and characterization of a class of DNA repair enzymes, DNA glycosylase/AP lyases, which are involved in base excision repair....
5.
Hilbert T, Chaung W, Boorstein R, Cunningham R, Teebor G
J Biol Chem
. 1997 Mar;
272(10):6733-40.
PMID: 9045706
We previously purified a bovine pyrimidine hydrate-thymine glycol DNA glycosylase/AP lyase. The amino acid sequence of tryptic bovine peptides was homologous to Escherichia coli endonuclease III, theoretical proteins of Saccharomyces...
6.
Hilbert T, Boorstein R, Kung H, Bolton P, Xing D, Cunningham R, et al.
Biochemistry
. 1996 Feb;
35(8):2505-11.
PMID: 8611553
We purified a homologue of the Escherichia coli DNA repair enzyme endo nuclease III 5000-fold from calf thymus which, like endonuclease III, demonstrates DNA-glycosylase activity against pyrimidine hydrates and thymine...
7.
Zuo S, Boorstein R, Cunningham R, Teebor G
Biochemistry
. 1995 Sep;
34(36):11582-90.
PMID: 7547889
We previously demonstrated the UV-induced formation of cytosine hydrate in DNA and its deamination product, uracil hydrate, via their release from the DNA backbone by the DNA glycosylase activity of...
8.
Zuo S, Boorstein R, Teebor G
Nucleic Acids Res
. 1995 Aug;
23(16):3239-43.
PMID: 7667100
Exposure of pyrimidines of DNA to ionizing radiation under aerobic conditions or oxidizing agents results in attack on the 5,6 double bond of the pyrimidine ring or on the exocyclic...
9.
ODonnell R, Boorstein R, Cunningham R, Teebor G
Biochemistry
. 1994 Aug;
33(33):9875-80.
PMID: 8060994
UV irradiation of cytosine yields 6-hydroxy-5,6-dihydrocytosine (cytosine hydrate) whether the cytosine is in solution as base, nucleoside, or nucleotide or on the DNA backbone. Cytosine hydrate decomposes by elimination of...
10.
Boorstein R, Chiu L, Teebor G
Mol Cell Biol
. 1992 Dec;
12(12):5536-40.
PMID: 1448084
We isolated a mutant mammalian cell line lacking activity for the DNA repair enzyme 5-hydroxymethyluracil-DNA glycosylase (HmUra-DNA glycosylase). The mutant was isolated through its resistance to the thymidine analog 5-hydroxymethyl-2'-deoxyuridine...