G van Meer
Overview
Explore the profile of G van Meer including associated specialties, affiliations and a list of published articles.
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Articles
79
Citations
3048
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Recent Articles
1.
Sprong H, Degroote S, Claessens T, van Drunen J, Oorschot V, Westerink B, et al.
J Cell Biol
. 2001 Oct;
155(3):369-80.
PMID: 11673476
Although glycosphingolipids are ubiquitously expressed and essential for multicellular organisms, surprisingly little is known about their intracellular functions. To explore the role of glycosphingolipids in membrane transport, we used the...
2.
Holthuis J, Pomorski T, Raggers R, Sprong H, van Meer G
Physiol Rev
. 2001 Oct;
81(4):1689-723.
PMID: 11581500
Eukaryotes are characterized by endomembranes that are connected by vesicular transport along secretory and endocytic pathways. The compositional differences between the various cellular membranes are maintained by sorting events, and...
3.
Raggers R, Vogels I, van Meer G
Biochem J
. 2001 Jul;
357(Pt 3):859-65.
PMID: 11463358
The human multidrug-resistance (MDR1) P-glycoprotein (Pgp) is an ATP-binding-cassette transporter (ABCB1) that is ubiquitously expressed. Often its concentration is high in the plasma membrane of cancer cells, where it causes...
4.
Sprong H, van der Sluijs P, van Meer G
Nat Rev Mol Cell Biol
. 2001 Jul;
2(7):504-13.
PMID: 11433364
Cells determine the bilayer characteristics of different membranes by tightly controlling their lipid composition. Local changes in the physical properties of bilayers, in turn, allow membrane deformation, and facilitate vesicle...
5.
Pomorski T, Hrafnsdottir S, Devaux P, van Meer G
Semin Cell Dev Biol
. 2001 Apr;
12(2):139-48.
PMID: 11292380
In eukaryotic cells, the membranes of different intracellular organelles have different lipid composition, and various biomembranes show an asymmetric distribution of lipid types across the membrane bilayer. Membrane lipid organization...
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Raggers R, Pomorski T, Holthuis J, Kalin N, van Meer G
Traffic
. 2001 Feb;
1(3):226-34.
PMID: 11208106
Membrane lipids do not spontaneously exchange between the two leaflets of lipid bilayers because the polar headgroups cannot cross the hydrophobic membrane interior. Cellular membranes, notably eukaryotic plasma membranes, are...
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