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G Sridhar Prasad

Explore the profile of G Sridhar Prasad including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 349
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Recent Articles
1.
Lai H, Sridhar Prasad G, Padmanabhan R
Antiviral Res . 2012 Nov; 97(1):74-80. PMID: 23127365
Four serotypes of dengue virus (DENV1-4), mosquito-borne members of Flaviviridae family cause frequent epidemics causing considerable morbidity and mortality in humans throughout tropical regions of the world. There is no...
2.
Su H, Yan Y, Sridhar Prasad G, Smith R, Daniels C, Abeywickrema P, et al.
J Virol . 2010 May; 84(15):7625-33. PMID: 20484498
HIV/AIDS continues to be a menace to public health. Several drugs currently on the market have successfully improved the ability to manage the viral burden in infected patients. However, new...
3.
Sparey T, Abeywickrema P, Almond S, Brandon N, Byrne N, Campbell A, et al.
Bioorg Med Chem Lett . 2008 May; 18(11):3386-91. PMID: 18455394
The 'NMDA hypofunction hypothesis of schizophrenia' can be tested in a number of ways. DAO is the enzyme primarily responsible for the metabolism of d-serine, a co-agonist for the NMDA...
4.
Aertgeerts K, Levin I, Shi L, Snell G, Jennings A, Sridhar Prasad G, et al.
J Biol Chem . 2005 Apr; 280(20):19441-4. PMID: 15809306
Fibroblast activation protein alpha (FAPalpha) is highly expressed in epithelial cancers and has been implicated in extracellular matrix remodeling, tumor growth, and metastasis. We present the first high resolution structure...
5.
Aertgeerts K, Ye S, Tennant M, Kraus M, Rogers J, Sang B, et al.
Protein Sci . 2004 Jan; 13(2):412-21. PMID: 14718659
Dipeptidyl peptidase IV (DPPIV) is a member of the prolyl oligopeptidase family of serine proteases. DPPIV removes dipeptides from the N terminus of substrates, including many chemokines, neuropeptides, and peptide...
6.
Sridhar Prasad G, Wahlberg M, Sridhar V, Sundaresan V, Yamaguchi M, Hatefi Y, et al.
Biochemistry . 2002 Oct; 41(42):12745-54. PMID: 12379117
Transhydrogenase (TH) is a dimeric integral membrane enzyme in mitochondria and prokaryotes that couples proton translocation across a membrane with hydride transfer between NAD(H) and NADP(H) in soluble domains. Crystal...
7.
Chen K, Jung Y, Bonagura C, Tilley G, Sridhar Prasad G, Sridhar V, et al.
J Biol Chem . 2001 Nov; 277(7):5603-10. PMID: 11704670
The reduction potential (E(0)') of the [4Fe-4S](2+/+) cluster of Azotobacter vinelandii ferredoxin I (AvFdI) and related ferredoxins is approximately 200 mV more negative than the corresponding clusters of Peptostreptococcus asaccharolyticus...
8.
Agalarov S, Sridhar Prasad G, Funke P, Stout C, Williamson J
Science . 2001 Feb; 288(5463):107-13. PMID: 10753109
The crystal structure of a 70-kilodalton ribonucleoprotein complex from the central domain of the Thermus thermophilus 30S ribosomal subunit was solved at 2.6 angstrom resolution. The complex consists of a...
9.
Sridhar Prasad G, Kresge N, Muhlberg A, Shaw A, Jung Y, Burgess B, et al.
Protein Sci . 1998 Dec; 7(12):2541-9. PMID: 9865948
NADPH:ferredoxin reductase (AvFPR) is involved in the response to oxidative stress in Azotobacter vinelandii. The crystal structure of AvFPR has been determined at 2.0 A resolution. The polypeptide fold is...