G Rudnick
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Explore the profile of G Rudnick including associated specialties, affiliations and a list of published articles.
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82
Citations
2001
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Recent Articles
1.
Alexander S, Benson H, Faccenda E, Pawson A, Sharman J, McGrath J, et al.
Br J Pharmacol
. 2014 Feb;
170(8):1449-58.
PMID: 24528237
The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of...
2.
Porton B, Greenberg B, Askland K, Serra L, Gesmonde J, Rudnick G, et al.
Transl Psychiatry
. 2013 May;
3:e259.
PMID: 23695234
The SLC1A1 gene, which encodes the neuronal glutamate transporter, EAAC1, has consistently been implicated in obsessive-compulsive disorder (OCD) in genetic studies. Moreover, neuroimaging, biochemical and clinical studies support a role...
3.
Castagna M, Soragna A, Mari S, Santacroce M, Bette S, Mandela P, et al.
Am J Physiol Cell Physiol
. 2007 Jul;
293(4):C1286-95.
PMID: 17626242
KAAT1 is a lepidopteran neutral amino acid transporter belonging to the NSS super family (SLC6), which has an unusual cation selectivity, being activated by K(+) and Li(+) in addition to...
4.
Rudnick G
Handb Exp Pharmacol
. 2006 May;
(175):59-73.
PMID: 16722230
Serotonin transporter (SERT) serves the important function of taking up serotonin (5-HT) released during serotonergic neurotransmission. It is the target for important therapeutic drugs and psychostimulants. SERT catalyzes the influx...
5.
Ozaki N, Goldman D, Kaye W, Plotnicov K, Greenberg B, Lappalainen J, et al.
Mol Psychiatry
. 2003 Nov;
8(11):933-6.
PMID: 14593431
Two common serotonin transporter (SERT) untranslated region gene variants have been intensively studied, but remain inconclusively linked to depression and other neuropsychiatric disorders. We now report an uncommon coding region...
6.
Kocabas A, Rudnick G, Kilic F
J Neurochem
. 2003 Jun;
85(6):1513-20.
PMID: 12787070
Before this study, the human norepinephrine transporter (hNET) was the only member of the biogenic amine neurotransmitter transporter family that had not been demonstrated to be a functional homo-oligomer. Here,...
7.
Gu H, Wu X, Giros B, Caron M, Caplan M, Rudnick G
Mol Biol Cell
. 2001 Dec;
12(12):3797-807.
PMID: 11739781
When expressed in epithelial cells, dopamine transporter (DAT) was detected predominantly in the apical plasma membrane, whereas norepinephrine transporter (NET) was found in the basolateral membrane, despite 67% overall amino...
8.
Androutsellis-Theotokis A, Ghassemi F, Rudnick G
J Biol Chem
. 2001 Oct;
276(49):45933-8.
PMID: 11592963
Serotonin transporter (SERT) contains a single reactive external cysteine residue at position 109 (Chen, J. G., Liu-Chen, S., and Rudnick, G. (1997) Biochemistry 36, 1479-1486) and seven predicted cytoplasmic cysteines....
9.
Ni Y, Chen J, Androutsellis-Theotokis A, Huang C, Moczydlowski E, Rudnick G
J Biol Chem
. 2001 Jun;
276(33):30942-7.
PMID: 11408487
Inactivation of serotonin transporter (SERT) expressed in HeLa cells by [2-(trimethylammonium)ethyl]methanethiosulfonate (MTSET) occurred much more readily when Na(+) in the reaction medium was replaced with Li(+). This did not result...
10.
Kamdar G, Penado K, Rudnick G, Stephan M
J Biol Chem
. 2000 Nov;
276(6):4038-45.
PMID: 11058600
Mutations at critical residue positions in transmembrane span 7 (TM7) of the serotonin transporter affect the Na(+) dependence of transport. It was possible that these residues, which form a stripe...