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G Ramafi

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Articles 8
Citations 73
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Recent Articles
1.
Ramafi G, Anderson R, Theron A, Feldman C, Taylor G, Wilson R, et al.
Pulm Pharmacol Ther . 2000 Nov; 13(6):293-9. PMID: 11061984
The effects of the intracellular adenosine 3':5' cyclic monophosphate (cAMP)-elevating agents, CGS 21680 (0.01- 1 microM) and rolipram (0.01-1 microM), as well as those of dibutyryl cAMP (0. 05-4 mM)...
2.
Visser S, Theron A, Ramafi G, Ker J, Anderson R
Biochem Pharmacol . 2000 Sep; 60(7):993-9. PMID: 10974209
This study was undertaken to identify the adenosine receptor (AR) subtypes which down-regulate the proinflammatory activities of human neutrophils, as well as the involvement of adenosine 3',5'-cyclic monophosphate (cAMP) and...
3.
Anderson R, Visser S, Ramafi G, Theron A
Br J Pharmacol . 2000 Jun; 130(4):717-24. PMID: 10864876
We have investigated the effects of the adenosine A(2A) receptor agonist CGS 21680 (0.01 - 1 microM) on reactive oxidant production by, and elastase release from FMLP-activated human neutrophils, as...
4.
Ramafi G, Anderson R, Theron A, Feldman C, Taylor G, Wilson R, et al.
Infect Immun . 1999 Sep; 67(10):5157-62. PMID: 10496890
The effects of pathologically relevant concentrations (0.38 to 12.5 microM) of the proinflammatory, Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine (1-hp) on Ca2+ metabolism and intracellular cyclic AMP (cAMP) in N-formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP; 1...
5.
Anderson R, Goolam Mahomed A, Theron A, Ramafi G, Feldman C
Br J Pharmacol . 1998 Jul; 124(3):547-55. PMID: 9647480
1. We have investigated the effects of the selective phosphodiesterase (PDE) type 4 inhibitor, rolipram (0.01-1 microM) on cytosolic Ca2+ fluxes in FMLP-activated human neutrophils, as well as on superoxide...
6.
Feldman C, Anderson R, Theron A, Ramafi G, COLE P, Wilson R
Inflammation . 1998 Jan; 21(6):655-65. PMID: 9429912
The effects of the bioactive phospholipids (PL), platelet-activating factor (PAF), lyso-PAF, and lysophosphatidylcholine (LPC) on the beat frequency and structural integrity of human ciliated respiratory epithelium were studied in vitro,...
7.
Anderson R, Ramafi G, Theron A
Biochem Pharmacol . 1996 Jul; 52(2):341-9. PMID: 8694859
We have investigated the effects of the beta-adrenoreceptor-blocking agent, propranolol (9-300 microM) on several pro-inflammatory activities of human neutrophils in vitro. Superoxide production by calcium ionophore (A23187)-activated neutrophils was particularly...
8.
Anderson R, Feldman C, Theron A, Ramafi G, COLE P, Wilson R
Br J Pharmacol . 1996 Apr; 117(7):1387-94. PMID: 8730730
1. We have investigated the effects of salmeterol (0.3-50 microM) on several pro-inflammatory activities of human neutrophils in vitro. 2. Oxidant production by FMLP- and calcium ionophore (A23187)-activated neutrophils was...