G M Edelman
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Explore the profile of G M Edelman including associated specialties, affiliations and a list of published articles.
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409
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13545
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Recent Articles
1.
Tononi G, Edelman G, Sporns O
Trends Cogn Sci
. 2011 Jan;
2(12):474-84.
PMID: 21227298
The brains of higher mammals are extraordinary integrative devices. Signals from large numbers of functionally specialized groups of neurons distributed over many brain regions are integrated to generate a coherent,...
2.
Tassin A, Mege R, Goudou D, Edelman G, Rieger F
Neurochem Int
. 2010 May;
18(1):97-106.
PMID: 20504682
We have studied the modulation of expression and surface distribution of the molecular forms of the neural cell adhesion molecule (N-CAM) during myogenesis in vitro. We found one minor and...
3.
Vanderklish P, Edelman G
Genes Brain Behav
. 2005 Aug;
4(6):360-84.
PMID: 16098135
Fragile X syndrome (FXS) is caused by the transcriptional silencing of the Fmr1 gene, which encodes a protein (FMRP) that can act as a translational suppressor in dendrites, and is...
4.
Sporns O, Tononi G, Edelman G
Behav Brain Res
. 2002 Oct;
135(1-2):69-74.
PMID: 12356436
Over recent years, a wealth of neuroanatomical information on the pattern of interconnections between segregated areas of the cerebral cortex has become available. Here, we describe a set of structural...
5.
Owens G, Mistry S, Edelman G, Crossin K
Gene Ther
. 2002 Jul;
9(15):1044-8.
PMID: 12101436
Treatments for nervous system disorders that involve transplanting genetically modified neural stem cells may ultimately be feasible. As a step towards this therapeutic approach, a novel murine embryonic stem cell...
6.
Schmitt-Ulms G, Legname G, Baldwin M, Ball H, Bradon N, Bosque P, et al.
J Mol Biol
. 2001 Dec;
314(5):1209-25.
PMID: 11743735
To identify molecular interaction partners of the cellular prion protein (PrP(C)), we sought to apply an in situ crosslinking method that maintains the microenvironment of PrP(C). Mild formaldehyde crosslinking of...
7.
Edelman G, Gally J
Proc Natl Acad Sci U S A
. 2001 Nov;
98(24):13763-8.
PMID: 11698650
Degeneracy, the ability of elements that are structurally different to perform the same function or yield the same output, is a well known characteristic of the genetic code and immune...
8.
Atkins A, Chung J, Deechongkit S, Little E, Edelman G, Wright P, et al.
J Mol Biol
. 2001 Jul;
311(1):161-72.
PMID: 11469865
Homophilic binding of the neural cell adhesion molecule (N-CAM) mediates the calcium-independent cell-cell adhesion that is involved in neuronal development. Two hypotheses have been advanced for the mechanism of homophilic...
9.
Pinkstaff J, Chappell S, Mauro V, Edelman G, Krushel L
Proc Natl Acad Sci U S A
. 2001 Feb;
98(5):2770-5.
PMID: 11226315
In neurons, translation of dendritically localized mRNAs is thought to play a role in affecting synaptic efficacy. Inasmuch as components of the translation machinery may be limiting in dendrites, we...
10.
Little E, Crossin K, Krushel L, Edelman G, Cunningham B
Proc Natl Acad Sci U S A
. 2001 Feb;
98(5):2238-43.
PMID: 11226223
The neural cell adhesion molecule (N-CAM) is expressed on the surface of astrocytes, where its homophilic binding leads to the activation of the transcription factor NF-kappaB. Transfection of astrocytes with...