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G M Brothers

Explore the profile of G M Brothers including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 2315
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Recent Articles
1.
de Vries L, Fischer T, Tronchere H, Brothers G, Strockbine B, Siderovski D, et al.
Proc Natl Acad Sci U S A . 2000 Dec; 97(26):14364-9. PMID: 11121039
Activator of G protein signaling 3 (AGS3) is a newly identified protein shown to act at the level of the G protein itself. AGS3 belongs to the GoLoco family of...
2.
Susin S, Lorenzo H, Zamzami N, Marzo I, Snow B, Brothers G, et al.
Nature . 1999 Feb; 397(6718):441-6. PMID: 9989411
Mitochondria play a key part in the regulation of apoptosis (cell death). Their intermembrane space contains several proteins that are liberated through the outer membrane in order to participate in...
3.
Snow B, Krumins A, Brothers G, Lee S, Wall M, Chung S, et al.
Proc Natl Acad Sci U S A . 1998 Oct; 95(22):13307-12. PMID: 9789084
Regulators of G protein signaling (RGS) proteins act as GTPase-activating proteins (GAPs) toward the alpha subunits of heterotrimeric, signal-transducing G proteins. RGS11 contains a G protein gamma subunit-like (GGL) domain...
4.
Stambolic V, Suzuki A, de la Pompa J, Brothers G, Mirtsos C, Sasaki T, et al.
Cell . 1998 Oct; 95(1):29-39. PMID: 9778245
PTEN is a tumor suppressor with sequence homology to protein tyrosine phosphatases and the cytoskeletal protein tensin. mPTEN-mutant mouse embryos display regions of increased proliferation. In contrast, mPTEN-deficient immortalized mouse...
5.
Ingi T, Krumins A, Chidiac P, Brothers G, Chung S, Snow B, et al.
J Neurosci . 1998 Sep; 18(18):7178-88. PMID: 9736641
Long-term neuronal plasticity is known to be dependent on rapid de novo synthesis of mRNA and protein, and recent studies provide insight into the molecules involved in this response. Here,...
6.
Snow B, Hall R, Krumins A, Brothers G, Bouchard D, Brothers C, et al.
J Biol Chem . 1998 Jul; 273(28):17749-55. PMID: 9651375
Regulator of G-protein signaling (RGS) proteins increase the intrinsic guanosine triphosphatase (GTPase) activity of G-protein alpha subunits in vitro, but how specific G-protein-coupled receptor systems are targeted for down-regulation by...