» Authors » G L Stiles

G L Stiles

Explore the profile of G L Stiles including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 115
Citations 2470
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Ji X, Stiles G, Jacobson K
Neurochem Int . 2010 May; 18(2):207-13. PMID: 20504695
The intrinsic affinity of 8-phenylxanthine analogs at striatal A(2)-adenosine receptors is highly species dependent. [(3)H]XAC (8-[2-aminoethyl[amino[carbonyl[methyl[oxyphenyl]]]]]-1,3-dipropylxanthine), although A(1)-selective in the rat brain, binds to A(2) receptors in rabbit striatal membranes...
2.
Olah M, Stiles G
Pharmacol Ther . 2000 Mar; 85(2):55-75. PMID: 10722120
Adenosine produces a wide variety of physiological effects through the activation of cell surface adenosine receptors (ARs). ARs are members of the G-protein-coupled receptor family, and currently, four subtypes, the...
3.
Palmer T, Stiles G
Mol Pharmacol . 2000 Feb; 57(3):539-45. PMID: 10692494
Activation of the A(3) adenosine receptor (A(3)AR) contributes to the cardioprotective, bronchoconstrictive, and hypotensive effects of adenosine. Agonist occupation of the A(3)AR results in a rapid desensitization of receptor function,...
4.
Palmer T, Stiles G
Biochemistry . 1999 Nov; 38(45):14833-42. PMID: 10555965
Activation of the A(2A) adenosine receptor (A(2A)AR) contributes to the neuromodulatory and neuroprotective effects of adenosine in the central nervous system. Here we demonstrate that, in rat C6 glioma cells...
5.
Xie R, Li A, Ji X, Melman N, Olah M, Stiles G, et al.
J Med Chem . 1999 Oct; 42(20):4232-8. PMID: 10514293
A(3) adenosine receptor antagonists are sought for their potential antiinflammatory, antiasthmatic, and antiischemic properties. We have found that 3,5-diacyl-1,2,4-trialkyl-6-phenylpyridinium derivatives constitute a novel class of selective A(3) adenosine receptor antagonists....
6.
Tilley A, Stiles G
Am Heart J . 1999 Sep; 138(3 Pt 1):390-1. PMID: 10467183
No abstract available.
7.
Ren H, Stiles G
Mol Pharmacol . 1999 Feb; 55(2):309-16. PMID: 9927623
The expression of the human A1 adenosine receptor gene is controlled by two promoters, promoters A and B, and they are located 600 base pairs apart. The characteristics of the...
8.
Nie Z, Mei Y, Ford M, Rybak L, Marcuzzi A, Ren H, et al.
Mol Pharmacol . 1998 May; 53(4):663-9. PMID: 9547356
The A1 adenosine receptor (A1AR) contributes to the cytoprotective action of adenosine under conditions known to generate reactive oxygen species (ROS). Pharmacological manipulation of A1AR expression has been shown to...
9.
Deckert J, Nothen M, Albus M, Franzek E, Rietschel M, Ren H, et al.
Am J Med Genet . 1998 Mar; 81(1):18-23. PMID: 9514582
In the present study we sought to identify genetic variation in the adenosine A1 receptor (A1AR) gene on chromosome 1q31-32.1, which through alteration of protein function or level of expression...
10.
Ren H, Stiles G
Mol Pharmacol . 1998 Jan; 53(1):43-51. PMID: 9443931
Human A1 adenosine receptor gene expression is controlled by two independent promoters. The upstream promoter, promoter A, is subject to tissue specific regulation because not all cells express the mRNA...