G L Moore
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Explore the profile of G L Moore including associated specialties, affiliations and a list of published articles.
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Articles
77
Citations
230
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Recent Articles
1.
Moore G, Greichus Y, Hugghins E
Bull Environ Contam Toxicol
. 2013 Nov;
3(5):269-73.
PMID: 24185303
No abstract available.
2.
Burgard A, Moore G, Maranas C
Metab Eng
. 2001 Oct;
3(4):285-8.
PMID: 11676564
No abstract available.
3.
Lutz S, Ostermeier M, Moore G, Maranas C, Benkovic S
Proc Natl Acad Sci U S A
. 2001 Sep;
98(20):11248-53.
PMID: 11562494
We have developed, experimentally implemented, and modeled in silico a methodology named SCRATCHY that enables the combinatorial engineering of target proteins, independent of sequence identity. The approach combines two methods...
4.
Miyake J, Doung X, Strauss W, Moore G, Castellani L, Curtiss L, et al.
J Biol Chem
. 2001 Apr;
276(26):23304-11.
PMID: 11323427
The finding that expression of a cholesterol 7alpha-hydroxylase (CYP7A1) transgene in cultured rat hepatoma cells caused a coordinate increase in lipogenesis and secretion of apoB-containing lipoproteins led to the hypothesis...
5.
Moore G, Maranas C, Lutz S, Benkovic S
Proc Natl Acad Sci U S A
. 2001 Mar;
98(6):3226-31.
PMID: 11248060
We introduce a quantitative framework for assessing the generation of crossovers in DNA shuffling experiments. The approach uses free energy calculations and complete sequence information to model the annealing process....
6.
Moore G, Maranas C
J Theor Biol
. 2000 Jul;
205(3):483-503.
PMID: 10882567
Directed evolution experiments rely on the cyclical application of mutagenesis, screening and amplification in a test tube. They have led to the creation of novel proteins for a wide range...
7.
Moore G, Drevon C, Machleder D, Trawick J, McClelland A, Roy S, et al.
Biochem J
. 1997 Jun;
324 ( Pt 3):863-7.
PMID: 9235879
Adenovirus is a vector for the delivery of genes mainly to the liver. Short-term (approximately 3 days) studies using adenovirus transfection have provided valuable insights into how genes can complement...
8.
Trawick J, Lewis K, Dueland S, Moore G, Simon F, Davis R
J Lipid Res
. 1996 Mar;
37(3):588-98.
PMID: 8728321
A stable hepatoma cell line (L35 cells) showing an activation of the cholesterol 7 alpha-hydroxylase gene (CYP7) that had been silent in the parental hepatoma cell line (H35 cells) was...
9.
Moore G, Hess J, Ledford M
Transfusion
. 1993 Sep;
33(9):709-12.
PMID: 8212114
An optimized additive solution was developed for the postthaw preservation of red cells that contained adenine, glucose, disodium phosphate, and citrate buffer. This solution, called AS-17, was compared to AS-3...
10.
Moore G, Zegna A, Ledford M, Huling J, Fishman R
Artif Organs
. 1992 Oct;
16(5):513-8.
PMID: 10078303
Many researchers are trying to develop a blood substitute based on chemically modified human hemoglobin. In the process of making such solutions, we were faced with the problem of determining...