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G Joone

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Articles 18
Citations 98
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Recent Articles
1.
Van Rensburg C, Joone G, Van Niekerk E, Anderson R
Ann N Y Acad Sci . 2000 Feb; 886:280-2. PMID: 10667239
No abstract available.
2.
Myer M, Joone G, Chasen M, Van Rensburg C
Oncol Rep . 1998 Dec; 6(1):217-8. PMID: 9864431
GF120918, at 250 ng/ml, increased the sensitivity of a P-glycoprotein (P-gp)-mediated multidrug resistant (MDR) small cell lung cancer cell line (H69/LX4) to the P-gp substrates, paclitaxel, taxotere, vinblastine, vinorelbine, daunorubicin...
3.
Van Rensburg C, Joone G, Anderson R
Cancer Lett . 1998 Jun; 127(1-2):107-12. PMID: 9619865
The effects of the membrane-stabilizing agent, alpha-tocopherol (25 microg/ml), on the chemosensitizing interactions of cyclosporin A (5 microg/ml), verapamil (2 microg/ml), clofazimine (1 microg/ml), B669 (0.5 microg/ml) and GF120918 (0.015...
4.
Van Rensburg C, Anderson R, Joone G, Myer M, OSullivan J
Anticancer Drugs . 1997 Aug; 8(7):708-13. PMID: 9311448
The multidrug resistance (MDR)-neutralizing and cytotoxic properties of 16 novel tetramethylpiperidine (TMP)-substituted phenazines were compared with those of clofazimine and B669 using a P-glycoprotein (P-gp)-expressing undifferentiated, human leukemia cell line...
5.
Ras G, Anderson R, Taylor G, SAVAGE J, Van Niekerk E, Joone G, et al.
Antimicrob Agents Chemother . 1992 Jun; 36(6):1236-40. PMID: 1329616
The Pseudomonas aeruginosa-derived phenazine pigments pyocyanin and 1-hydroxyphenazine (1-hp) prime human neutrophils for enhanced, stimulus-activated release of superoxide and myeloperoxidase (MPO), respectively. In the present study, the modulatory potentials of...
6.
Van Rensburg C, Joone G, Anderson R
J Med Microbiol . 1990 May; 32(1):15-7. PMID: 2111406
The effect of the O2-dependent antimicrobial systems of the human neutrophil on the intraphagocytic activity of difloxacin, ciprofloxacin, pefloxacin and fleroxacin was determined by use of a radioassay with Staphylococcus...
7.
Van Rensburg C, Joone G, Anderson R
Chemotherapy . 1989 Jan; 35(4):273-7. PMID: 2504545
In this study the intraphagocytic bioactivity of difloxacin, ciprofloxacin, pefloxacin and fleroxacin was investigated using human neutrophils and a combination of a radioassay, a colony-counting method and a fluorescence microassay...
8.
Anderson R, Joone G, Van Rensburg C
J Antimicrob Chemother . 1988 Dec; 22(6):923-33. PMID: 2977384
Erythromycin base and its 6-0-methyl derivative clarithromycin were actively accumulated 7.3 +/- 1.2-fold and 9.2 +/- 2-fold respectively by human neutrophils in vitro. The intraphagocytic bioactivities of the antimicrobial agents...
9.
Anderson R, Van Rensburg C, Joone G, Lukey P
J Antimicrob Chemother . 1987 Nov; 20 Suppl B:57-68. PMID: 3429387
The binding to human polymorphonuclear leucocytes and the intracellular bioactivity of the macrolide antibiotics erythromycin and roxithromycin on Legionella micdadei, Listeria monocytogenes and Staphylococcus aureus were investigated in vitro by...
10.
Anderson R, Joone G, Van Rensburg C
J Infect Dis . 1986 Mar; 153(3):593-600. PMID: 3950443
The intraphagocytic bioactivities for Staphylococcus aureus of amoxicillin, clindamycin, and erythromycin (0.0075-20 micrograms/ml) were measured in human polymorphonuclear leukocytes (PMNLs) with the combination of a fluorochrome microassay and a radioassay....