G J Stevens
Overview
Explore the profile of G J Stevens including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
26
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Potts B, Deese A, Stevens G, Reily M, Robertson D, Theiss J
J Pharm Biomed Anal
. 2001 Aug;
26(3):463-76.
PMID: 11489392
The ability to interpret metabolic responses to toxic insult as expressed in altered urine composition and measured by NMR spectroscopy is dependent upon a database of proton NMR spectra of...
2.
Stevens G, Burkey J, McQueen C
Cell Biol Toxicol
. 2000 Jul;
16(1):31-9.
PMID: 10890504
The heterocyclic amine, batracylin (BAT), is genotoxic and several lines of evidence suggest that acetylation is one step in the formation of a DNA-damaging product. The variation in susceptibility to...
3.
Stevens G, Payton M, Sim E, McQueen C
Drug Metab Dispos
. 1999 Aug;
27(9):966-71.
PMID: 10460792
Batracylin (8-aminoisoindolo[1,2-b]quinazolin-12(10 H)-one; BAT) is a heterocyclic amine that exhibits antitumor activity in a number of in vivo and in vitro models. The acetyl product has been implicated in BAT...
4.
Liu J, Stevens G, KRANER J, Fontaine S, Halpert J, Sipes I
Drug Metab Dispos
. 1999 Feb;
27(2):281-7.
PMID: 9929517
4-Vinylcyclohexene (VCH), an ovarian toxicant in mice, is known to irreversibly deplete ovarian follicles as a consequence of VCH diepoxide formation. Because ovotoxicity requires repeated dosing of VCH, the effect...
5.
Stevens G, Hitchcock K, Wang Y, Coppola G, Versace R, Chin J, et al.
Chem Res Toxicol
. 1997 Jul;
10(7):733-41.
PMID: 9250406
The in vitro metabolism of SDZ HDL 376, a thiocarbamide developed for the treatment of atherosclerosis, was investigated in rat, dog, monkey, and human liver microsomes, as well as in...
6.
Stevens G, LaVoie E, McQueen C
Carcinogenesis
. 1996 Jan;
17(1):115-9.
PMID: 8565119
The role of acetylation in the genotoxicity of the heterocyclic amine, batracylin, was evaluated in Salmonella typhimurium strains expressing various levels of N- and O-acetyltransferase activity. A significant correlation was...
7.
Meegalla S, Stevens G, McQueen C, Chen A, Yu C, Liu L, et al.
J Med Chem
. 1994 Sep;
37(20):3434-9.
PMID: 7932571
The synthesis and pharmacological activity of isoindolo[1,2-b]quinazolin-12(10H)-ones and isoindolo[2,1-a]benzimidazoles related to batracylin are described. The acute toxicity of batracyclin has been associated with the formation of its N-acetyl metabolite which...
8.
Stevens G, McQueen C
Toxicol Appl Pharmacol
. 1994 May;
126(1):39-44.
PMID: 8184431
Batracylin (8-aminoisoindolo[1,2-b]quinazolin-12(10H)-one), an experimental chemotherapeutic agent, is a heterocyclic aryl amine. The presence of the free amino group suggests that this compound may be a carcinogen. Since many carcinogens or...
9.
Stapleton S, Stevens G, Teel J, Rank K, BERG E, Wu J, et al.
Biochimie
. 1993 Jan;
75(11):971-6.
PMID: 8123704
Ethanol has been shown to induce the activity of glucose-6-phosphate dehydrogenase (G6PDH). To clarify the mechanism behind this induction, we examined the role of acetaldehyde (AA), the first product of...
10.