G J Leclerc
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Explore the profile of G J Leclerc including associated specialties, affiliations and a list of published articles.
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3
Citations
73
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0
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Recent Articles
1.
Leclerc G, Mou C, Leclerc G, Mian A, Barredo J
Leukemia
. 2010 Jan;
24(3):552-62.
PMID: 20072153
Children with acute lymphoblastic leukemia (ALL) diagnosed with resistant phenotypes, and those who relapse, have a dismal prognosis for cure. The antifolate methotrexate (MTX), a universal component of ALL therapies,...
2.
Leclerc G, Barredo J
Clin Cancer Res
. 2001 Apr;
7(4):942-51.
PMID: 11309345
Folypoly-gamma-glutamate synthetase (FPGS) is essential for the cytotoxicity of "classical" antifolates and their efficacy in cancer chemotherapy. The expression of the FPGS gene appears controlled by both tissue/lineage-specific and proliferation-dependent...
3.
Leclerc G, Tartera C, Metcalf E
Infect Immun
. 1998 Feb;
66(2):682-91.
PMID: 9453627
Salmonella typhi is the etiologic agent of human typhoid. During infection, S. typhi adheres to and invades epithelial and M cells that line the distal ileum. To survive in the...