G J Kaczorowski
Overview
Explore the profile of G J Kaczorowski including associated specialties, affiliations and a list of published articles.
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99
Citations
2581
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Recent Articles
11.
Suarez-Kurtz G, Vianna-Jorge R, Pereira B, Garcia M, Kaczorowski G
J Pharmacol Exp Ther
. 1999 May;
289(3):1517-22.
PMID: 10336547
Potent and selective peptidyl blockers of the Shaker-type (Kv1) voltage-gated potassium channels were used to determine the role of these channels in regulating the spontaneous motility of smooth muscle preparations....
12.
Wanner S, Koch R, Koschak A, Trieb M, Garcia M, Kaczorowski G, et al.
Biochemistry
. 1999 Apr;
38(17):5392-400.
PMID: 10220326
In rat brain, high-conductance Ca2+-activated K+ (BK) channels are targeted to axons and nerve terminals [Knaus, H. G., et al. (1996) J. Neurosci. 16, 955-963], but absolute levels of their...
13.
Felix J, Bugianesi R, Schmalhofer W, Borris R, Goetz M, Hensens O, et al.
Biochemistry
. 1999 Apr;
38(16):4922-30.
PMID: 10213593
A novel nortriterpene, termed correolide, purified from the tree Spachea correae, inhibits Kv1.3, a Shaker-type delayed rectifier potassium channel present in human T lymphocytes. Correolide inhibits 86Rb+ efflux through Kv1.3...
14.
Garcia M, Hanner M, Knaus H, Slaughter R, Kaczorowski G
Methods Enzymol
. 1999 Jan;
294:624-39.
PMID: 9916251
The search for peptidyl inhibitors of K+ channels is a very active area of investigation. In addition to scorpion venoms, other venom sources have been investigated; all of these sources...
15.
Garcia M, Giangiacomo K, Hanner M, Knaus H, McManus O, Schmalhofer W, et al.
Methods Enzymol
. 1999 Jan;
294:274-87.
PMID: 9916233
No abstract available.
16.
Garcia M, Hanner M, Kaczorowski G
Toxicon
. 1998 Oct;
36(11):1641-50.
PMID: 9792181
Over the last period of time, a large number of scorpion toxins have been characterized. These peptidyl inhibitors of K+ channels have been very useful as probes for determining the...
17.
Hanner M, Vianna-Jorge R, Kamassah A, Schmalhofer W, Knaus H, Kaczorowski G, et al.
J Biol Chem
. 1998 Jun;
273(26):16289-96.
PMID: 9632689
Coexpression of alpha and beta subunits of the high conductance Ca2+-activated K+ (maxi-K) channel leads to a 50-fold increase in the affinity for 125I-charybdotoxin (125I-ChTX) as compared with when the...
18.
Koschak A, Bugianesi R, Mitterdorfer J, Kaczorowski G, Garcia M, Knaus H
J Biol Chem
. 1998 Feb;
273(5):2639-44.
PMID: 9446567
Five novel peptidyl inhibitors of Shaker-type (Kv1) K+ channels have been purified to homogeneity from venom of the scorpion Centruroides limbatus. The complete primary amino acid sequence of the major...
19.
Suarez-Kurtz G, Nascimento J, Ondeyka J, Kaczorowski G
Eur J Pharmacol
. 1997 Nov;
335(2-3):153-9.
PMID: 9369368
Isometric tension recordings and patch-clamp methods were combined to explore the functional effects and mechanisms of action of 8-daucene-3,4-diol (CAF603), a carotane sesquiterpene isolated from the fungus Trichoderma virens. CAF603...
20.
Koch R, Wanner S, Koschak A, Hanner M, Schwarzer C, Kaczorowski G, et al.
J Biol Chem
. 1997 Nov;
272(44):27577-81.
PMID: 9346893
Neurons require specific patterns of K+ channel subunit expression as well as the precise coassembly of channel subunits into heterotetrameric structures for proper integration and transmission of electrical signals. In...