G J Im
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Explore the profile of G J Im including associated specialties, affiliations and a list of published articles.
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19
Citations
162
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Recent Articles
1.
Im G, Jung H
J Laryngol Otol
. 2007 May;
122(3):310-3.
PMID: 17524175
Cogan's syndrome is a rare clinical entity that is characterised by non-syphilitic interstitial keratitis and audiovestibular symptoms. The cause of Cogan's syndrome is considered to be autoimmune disease, which is...
2.
Park B, Kyung K, Choi J, Im G, Kim I, Shim J
Bull Environ Contam Toxicol
. 2006 Jan;
75(5):937-44.
PMID: 16400582
No abstract available.
3.
Kim D, Lee J, Lee N, Ryu D, Kim J, Lee S, et al.
Bioorg Med Chem
. 2001 Oct;
9(11):3013-21.
PMID: 11597484
New sildenafil analogues possessing a carboxylic acid group in the 5'-sulfonamide of the phenyl ring, 9a-l, were prepared from the readily available starting compounds 6a-b and cyclic amines 3-5 in...
4.
Kim D, Ryu D, Lee N, Lee J, Kim J, Lee S, et al.
Bioorg Med Chem
. 2001 Jun;
9(7):1895-9.
PMID: 11425592
New sildenafil analogues with an N-acylamido group at the 5'-position of the phenyl ring, 6a--e, were prepared from the readily available starting compound 2 in four straightforward steps. Enzyme assays...
5.
Choi W, Im G, Kim D, Kim T, Jung I, Kim T, et al.
Drug Metab Dispos
. 2001 Jun;
29(7):945-9.
PMID: 11408358
2-Amino-9-(3-acetoxymethyl-4-isopropoxycarbonyloxybut-1-yl)- purine (SK1899) was tested as an oral prodrug for penciclovir. SK1899 was administered orally to rats and dogs at doses up to 2 and 0.68 mmol/kg, respectively. SK1899 was...
6.
Kim D, Lee N, Lee J, Ryu D, Kim J, Lee S, et al.
Bioorg Med Chem
. 2001 Jun;
9(6):1609-16.
PMID: 11408180
New sildenafil analogues containing an ether ring fused into the phenyl moiety, 6a--d and 7a--d, were efficiently synthesized from the readily available starting materials, 1a--d and 2, in five steps....
7.
Kim D, Ryu D, Lee J, Lee N, Kim Y, Kim J, et al.
J Med Chem
. 2001 May;
44(10):1594-602.
PMID: 11334569
Eleven A-ring modified hexacyclic analogues of camptothecin (CPT) containing a 1,4-oxazine ring were synthesized from 10-hydroxycamptothecin (11a) and 7-ethyl-10-hydroxycamptothecin (3) (SN-38) in four to five steps and were subjected to...
8.
Ryu K, Rhee H, Jung I, Kim T, Lee S, Im G, et al.
Arzneimittelforschung
. 2000 May;
50(4):395-403.
PMID: 10800640
The general pharmacological properties of 2-amino-9-(3-acetoxymethyl-4-isopropoxycarbonyloxybut-1-yl)purine (CAS 247081-81-8, SK 1899), a new potential antiviral agent, were investigated in mice, rats, guinea pigs, rabbits, and dogs. The oral administration of 50,...
9.
Kim D, Lee N, Ryu D, Kim Y, Kim J, Chang K, et al.
Bioorg Med Chem
. 1999 Sep;
7(8):1715-25.
PMID: 10482463
A series of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purin es (1-8) and 2-amino-9-(3-alkoxycarbonyl-oxymethyl-4-alkoxycarbonyloxybut -1-yl)purines (9-12) were synthesized as potential prodrugs of penciclovir. Treatment of 6-deoxypenciclovir with trimethyl orthoacetate or triethyl orthopropionate (1.2 equiv) in DMF...
10.
Kim D, Lee N, Kim H, Im G, Kim K
Bioorg Med Chem
. 1999 Apr;
7(3):565-70.
PMID: 10220040
2-Amino-6-fluoro-9-(4-hydroxy-3-hydroxymethylbut-1-yl)purine (7), and its mono- and diesters 8-15 were prepared and evaluated for their potential as prodrugs of penciclovir. Treatment of 2-amino-6-chloro-9-(4-hydroxy-3-hydroxymethylbut-1-yl)purine (5) with trimethylamine in THF followed by a...