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G G Reinholz

Explore the profile of G G Reinholz including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 318
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Recent Articles
1.
Mrosek E, Chung H, Fitzsimmons J, ODriscoll S, Reinholz G, Schagemann J
Bone Joint Res . 2016 Sep; 5(9):403-11. PMID: 27660334
Objectives: We sought to determine if a durable bilayer implant composed of trabecular metal with autologous periosteum on top would be suitable to reconstitute large osteochondral defects. This design would...
2.
Schagemann J, Paul S, Casper M, Rohwedel J, Kramer J, Kaps C, et al.
J Biomed Mater Res A . 2012 Nov; 101(6):1620-8. PMID: 23184542
The objective of this study was to develop a scaffold for mesenchymal stromal cell (MSC) recruitment, proliferation, and chondrogenic differentiation. The concept behind the design is to mimic the cartilage...
3.
Olivos-Meza A, Fitzsimmons J, Casper M, Chen Q, An K, Ruesink T, et al.
Osteoarthritis Cartilage . 2010 Jul; 18(9):1183-91. PMID: 20633683
Objective: To compare the efficacy of in situ transforming growth factor-beta1 (TGF-beta1)-pretreated periosteum to untreated periosteum for regeneration of osteochondral tissue in rabbits. Methods: In the pretreatment group, 12 month-old...
4.
Casper M, Fitzsimmons J, Stone J, Meza A, Huang Y, Ruesink T, et al.
Osteoarthritis Cartilage . 2010 May; 18(7):981-91. PMID: 20434575
Objective: To determine the potential of periosteal cells to infiltrate poly-epsilon-caprolactone (PCL) nanofiber scaffolds in vivo and subsequently produce cartilage in vitro. Design: PCL nanofiber scaffolds, with or without chitosan-coating...
5.
Schagemann J, Chung H, Mrosek E, Stone J, Fitzsimmons J, ODriscoll S, et al.
J Biomed Mater Res A . 2009 Jul; 93(2):454-63. PMID: 19582837
The aim of this study was to determine the suitability of hybrid scaffolds composed of naturally derived biopolymer gels and macroporous poly-epsilon-caprolactone (PCL) scaffolds for neocartilage formation in vitro. Rabbit...
6.
Reinholz G, Fitzsimmons J, Casper M, Ruesink T, Chung H, Schagemann J, et al.
Osteoarthritis Cartilage . 2008 Dec; 17(6):723-34. PMID: 19064326
Objective: To examine the potential for rejuvenation of aged periosteum by local injection of transforming growth factor-beta1 (TGF-beta1) and insulin-like growth factor-1 (IGF-1) alone or in combination to induce cambium...
7.
Reinholz G, Lu L, Saris D, Yaszemski M, ODriscoll S
Biomaterials . 2003 Dec; 25(9):1511-21. PMID: 14697854
Animal models are widely used to develop and evaluate tissue-engineering techniques for the reconstruction of damaged human articular cartilage. For the purpose of this review, these model systems will include...
8.
Fukumoto T, Sperling J, Sanyal A, Fitzsimmons J, Reinholz G, Conover C, et al.
Osteoarthritis Cartilage . 2002 Dec; 11(1):55-64. PMID: 12505488
Objective: Periosteum contains undifferentiated mesenchymal stem cells that have both chondrogenic and osteogenic potential, and has been used to repair articular cartilage defects. During this process, the role of growth...
9.
Reinholz G, Getz B, Pederson L, Sanders E, Subramaniam M, Ingle J, et al.
Cancer Res . 2000 Nov; 60(21):6001-7. PMID: 11085520
Bisphosphonates are widely used clinically to treat bone diseases in which bone resorption is in excess. However, the mechanism of bisphosphonate action on bone is not fully understood. Studies of...
10.
Zierold C, Reinholz G, Mings J, Prahl J, DeLuca H
Arch Biochem Biophys . 2000 Oct; 381(2):323-7. PMID: 11032422
The 24-hydroxylase is the enzyme responsible for the first step in the catabolism of 1,25-dihydroxyvitamin D3, the active form of vitamin D. This enzyme was shown to be upregulated by...