G C Shore
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Explore the profile of G C Shore including associated specialties, affiliations and a list of published articles.
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1846
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Recent Articles
11.
Nguyen M, Branton P, Roy S, Nicholson D, Alnemri E, Yeh W, et al.
J Biol Chem
. 1998 Dec;
273(50):33099-102.
PMID: 9837871
Expression of the 243-residue form of the adenovirus E1A protein in the absence of other viral proteins triggers apoptosis by a pathway that requires p53. This pathway includes processing and...
12.
Granville D, Carthy C, Jiang H, Shore G, McManus B, Hunt D
FEBS Lett
. 1998 Nov;
437(1-2):5-10.
PMID: 9804161
Photodynamic therapy (PDT) is a clinical approach that utilizes light-activated drugs for the treatment of a variety of pathologic conditions. The initiating events of PDT-induced apoptosis are poorly defined. It...
13.
Goping I, Gross A, Lavoie J, Nguyen M, Jemmerson R, Roth K, et al.
J Cell Biol
. 1998 Oct;
143(1):207-15.
PMID: 9763432
The proapoptotic protein BAX contains a single predicted transmembrane domain at its COOH terminus. In unstimulated cells, BAX is located in the cytosol and in peripheral association with intracellular membranes...
14.
Marcellus R, Lavoie J, Boivin D, Shore G, Ketner G, Branton P
J Virol
. 1998 Aug;
72(9):7144-53.
PMID: 9696808
Previous studies by our group showed that infection of human and rodent cells by human adenovirus type 5 (Ad5) results in the induction of p53-independent apoptosis and cell death that...
15.
Lavoie J, Nguyen M, Marcellus R, Branton P, Shore G
J Cell Biol
. 1998 Mar;
140(3):637-45.
PMID: 9456323
In the absence of E1B, the 289-amino acid product of human adenovirus type 5 13S E1A induces p53-independent apoptosis by a mechanism that requires viral E4 gene products (Marcellus, R.C.,...
16.
Ng F, Shore G
J Biol Chem
. 1998 Mar;
273(6):3140-3.
PMID: 9452422
Bap31 is a polytopic integral membrane protein of the endoplasmic reticulum and forms a complex with Bcl-2/Bcl-XL and procaspase-8 (Ng, F. W. H., Nguyen, M., Kwan, T., Branton, P. E.,...
17.
Steenaart N, Shore G
FEBS Lett
. 1997 Nov;
415(3):294-8.
PMID: 9357986
This study was undertaken to identify novel mitochondrial membrane proteins that are potential targets for phosphorylation. Mitochondrial membranes were incubated in the presence of [gamma-32P]ATP and the Triton X-114 extractable...
18.
Ng F, Nguyen M, Kwan T, Branton P, Nicholson D, Cromlish J, et al.
J Cell Biol
. 1997 Oct;
139(2):327-38.
PMID: 9334338
We have identified a human Bcl-2-interacting protein, p28 Bap31. It is a 28-kD (p28) polytopic integral protein of the endoplasmic reticulum whose COOH-terminal cytosolic region contains overlapping predicted leucine zipper...
19.
Schleiff E, Shore G, Goping I
J Biol Chem
. 1997 Jul;
272(28):17784-9.
PMID: 9211931
Tom20 is part of a multiple component, dynamic complex that functions to import specific cytosolic proteins into or through the outer membrane of the mitochondrion. To analyze the contribution of...
20.
Steenaart N, Shore G
J Biol Chem
. 1997 May;
272(18):12057-61.
PMID: 9115273
Tom70p is targeted and inserted into the mitochondrial outer membrane in the Nin-Ccyto orientation, via an NH2-terminal signal anchor sequence. The signal anchor is comprised of two domains: an NH2-terminal...