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G Bergers

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Articles 16
Citations 2676
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Recent Articles
1.
White K, Connor K, Meylan M, Bougouin A, Salvucci M, Bielle F, et al.
Ann Oncol . 2022 Dec; 34(3):300-314. PMID: 36494005
Background: New precision medicine therapies are urgently required for glioblastoma (GBM). However, to date, efforts to subtype patients based on molecular profiles have failed to direct treatment strategies. We hypothesised...
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Blouw B, Haase V, Song H, Bergers G, Johnson R
Oncogene . 2007 Feb; 26(31):4531-40. PMID: 17297464
Individuals bearing germ line mutations in the Von Hippel-Lindau (VHL) tumor suppressor gene are predisposed to the development of highly angiogenic tumors. This is correlated with an increased expression of...
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Toft D, Rosenberg S, Bergers G, Volpert O, Linzer D
Proc Natl Acad Sci U S A . 2001 Oct; 98(23):13055-9. PMID: 11606769
Proliferin (PLF) is an angiogenic placental hormone. We now report that PLF gene expression can also occur in a progressive fibrosarcoma mouse tumor cell model. PLF mRNA and protein are...
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Bergers G, Hanahan D
Nat Biotechnol . 2001 Jan; 19(1):20-1. PMID: 11135544
No abstract available.
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Bergers G, Brekken R, McMahon G, Vu T, Itoh T, Tamaki K, et al.
Nat Cell Biol . 2000 Oct; 2(10):737-44. PMID: 11025665
During carcinogenesis of pancreatic islets in transgenic mice, an angiogenic switch activates the quiescent vasculature. Paradoxically, vascular endothelial growth factor (VEGF) and its receptors are expressed constitutively. Nevertheless, a synthetic...
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Hanahan D, Bergers G, Bergsland E
J Clin Invest . 2000 Apr; 105(8):1045-7. PMID: 10772648
No abstract available.
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Bergers G, Coussens L
Curr Opin Genet Dev . 2000 Feb; 10(1):120-7. PMID: 10679388
Extracellular metal-dependent proteinases regulate cell behavior by remodeling stromal and cell surface proteins, thereby influencing cell recruitment, cell shape, motility, proliferation, survival, genomic (in)stability, and differentiation. In recent years, the...
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Coussens L, Raymond W, Bergers G, Behrendtsen O, Werb Z, Caughey G, et al.
Genes Dev . 1999 Jun; 13(11):1382-97. PMID: 10364156
Expression of HPV16 early region genes in basal keratinocytes of transgenic mice elicits a multistage pathway to squamous carcinoma. We report that infiltration by mast cells and activation of the...
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Bergers G, Javaherian K, Lo K, Folkman J, Hanahan D
Science . 1999 Apr; 284(5415):808-12. PMID: 10221914
Solid tumors depend on angiogenesis for their growth. In a transgenic mouse model of pancreatic islet cell carcinogenesis (RIP1-Tag2), an angiogenic switch occurs in premalignant lesions, and angiogenesis persists during...