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Fuyuan Jing

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Articles 9
Citations 163
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Recent Articles
1.
Jing F, Chen K, Yandeau-Nelson M, Nikolau B
Front Bioeng Biotechnol . 2024 Apr; 12:1379121. PMID: 38665811
Modulating the catalytic activity of acyl-ACP thioesterase (TE) is an important biotechnological target for effectively increasing flux and diversifying products of the fatty acid biosynthesis pathway. In this study, a...
2.
Zou J, Jing F
Pharmaceuticals (Basel) . 2022 Dec; 15(12). PMID: 36558922
Little is known about cardiovascular safety profiles for monoclonal antibody products that received the FDA Emergency Use Authorization for COVID-19. In this study, data from the FDA Adverse Event Reporting...
3.
Jing F, Yandeau-Nelson M, Nikolau B
Biochem J . 2018 Nov; 475(23):3861-3873. PMID: 30409825
In plants and bacteria that use a Type II fatty acid synthase, isozymes of acyl-acyl carrier protein (ACP) thioesterase (TE) hydrolyze the thioester bond of acyl-ACPs, terminating the process of...
4.
Jing F, Zhao L, Yandeau-Nelson M, Nikolau B
Nat Commun . 2018 Mar; 9(1):860. PMID: 29491418
The substrate specificity of acyl-ACP thioesterase (TE) plays an essential role in controlling the fatty acid profile produced by type II fatty acid synthases. Here we identify two groups of...
5.
Garg S, Rizhsky L, Jin H, Yu X, Jing F, Yandeau-Nelson M, et al.
Metab Eng . 2016 Feb; 35:9-20. PMID: 26827988
Fatty acids that are chemically functionalized at their ω-ends are rare in nature yet offer unique chemical and physical properties with wide ranging industrial applications as feedstocks for bio-based polymers,...
6.
Marcella A, Jing F, Barb A
Protein Expr Purif . 2015 May; 115:39-45. PMID: 26008118
The fatty acid biosynthetic pathway generates highly reduced carbon based molecules. For this reason fatty acid synthesis is a target of pathway engineering to produce novel specialty or commodity chemicals...
7.
Wang Y, Yang K, Jing F, Li M, Deng T, Huang R, et al.
Mol Biol (Mosk) . 2012 Mar; 45(5):817-24. PMID: 22393777
Artemisinin, a sesquiterpene lactone endoperoxide derived from Artemisia annua L. (Asteraceae), is the most effective antimalarial drug. We used two methods: genome walking and thermal asymmetric interlaced polymerase chain reaction,...
8.
Jing F, Cantu D, Tvaruzkova J, Chipman J, Nikolau B, Yandeau-Nelson M, et al.
BMC Biochem . 2011 Aug; 12:44. PMID: 21831316
Background: Acyl-acyl carrier protein thioesterases (acyl-ACP TEs) catalyze the hydrolysis of the thioester bond that links the acyl chain to the sulfhydryl group of the phosphopantetheine prosthetic group of ACP....
9.
Zhang L, Jing F, Li F, Li M, Wang Y, Wang G, et al.
Biotechnol Appl Biochem . 2008 Jun; 52(Pt 3):199-207. PMID: 18564056
Artemisinin is an effective anti-malarial drug isolated from Artemisia annua L. (Chinese wormwood), but the content of artemisinin in A. annua is low. In the present study we explored the...